Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human)) | BDBM50291707 ((S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Organon K.K. Curated by ChEMBL | Assay Description Inhibition of heparin-binding epidermal growth factor (HB-EGF) shedding | J Med Chem 45: 930-6 (2002) BindingDB Entry DOI: 10.7270/Q2QV3KS7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amphiregulin (Homo sapiens (Human)) | BDBM50291707 ((S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquin...) | PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
Organon K.K. Curated by ChEMBL | Assay Description In vitro amphiregulin shedding inhibition | J Med Chem 45: 930-6 (2002) BindingDB Entry DOI: 10.7270/Q2QV3KS7 | |||||||||||
More data for this Ligand-Target Pair |