Found 6 hits of ic50 for monomerid = 50301104 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50301104
((5S,6S)-5-(hydroxycarbamoyl)-6-(4-phenyl-1,2,3,6-t...)Show SMILES ONC(=O)[C@H]1CC(CN[C@@H]1C(=O)N1CCC(=CC1)c1ccccc1)OC(=O)N1CCCC1 |r,c:16| Show InChI InChI=1S/C23H30N4O5/c28-21(25-31)19-14-18(32-23(30)27-10-4-5-11-27)15-24-20(19)22(29)26-12-8-17(9-13-26)16-6-2-1-3-7-16/h1-3,6-8,18-20,24,31H,4-5,9-15H2,(H,25,28)/t18?,19-,20-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Incyte Corporation
Curated by ChEMBL
| Assay Description Inhibition of HER-2 |
Bioorg Med Chem Lett 19: 5037-42 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S |
More data for this Ligand-Target Pair | |
Disintegrin and metalloproteinase domain-containing protein 10
(Homo sapiens (Human)) | BDBM50301104
((5S,6S)-5-(hydroxycarbamoyl)-6-(4-phenyl-1,2,3,6-t...)Show SMILES ONC(=O)[C@H]1CC(CN[C@@H]1C(=O)N1CCC(=CC1)c1ccccc1)OC(=O)N1CCCC1 |r,c:16| Show InChI InChI=1S/C23H30N4O5/c28-21(25-31)19-14-18(32-23(30)27-10-4-5-11-27)15-24-20(19)22(29)26-12-8-17(9-13-26)16-6-2-1-3-7-16/h1-3,6-8,18-20,24,31H,4-5,9-15H2,(H,25,28)/t18?,19-,20-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Incyte Corporation
Curated by ChEMBL
| Assay Description Inhibition of ADAM-10 |
Bioorg Med Chem Lett 19: 5037-42 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50301104
((5S,6S)-5-(hydroxycarbamoyl)-6-(4-phenyl-1,2,3,6-t...)Show SMILES ONC(=O)[C@H]1CC(CN[C@@H]1C(=O)N1CCC(=CC1)c1ccccc1)OC(=O)N1CCCC1 |r,c:16| Show InChI InChI=1S/C23H30N4O5/c28-21(25-31)19-14-18(32-23(30)27-10-4-5-11-27)15-24-20(19)22(29)26-12-8-17(9-13-26)16-6-2-1-3-7-16/h1-3,6-8,18-20,24,31H,4-5,9-15H2,(H,25,28)/t18?,19-,20-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 102 | n/a | n/a | n/a | n/a | n/a | n/a |
Incyte Corporation
Curated by ChEMBL
| Assay Description Inhibition of MMP-2 |
Bioorg Med Chem Lett 19: 5037-42 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50301104
((5S,6S)-5-(hydroxycarbamoyl)-6-(4-phenyl-1,2,3,6-t...)Show SMILES ONC(=O)[C@H]1CC(CN[C@@H]1C(=O)N1CCC(=CC1)c1ccccc1)OC(=O)N1CCCC1 |r,c:16| Show InChI InChI=1S/C23H30N4O5/c28-21(25-31)19-14-18(32-23(30)27-10-4-5-11-27)15-24-20(19)22(29)26-12-8-17(9-13-26)16-6-2-1-3-7-16/h1-3,6-8,18-20,24,31H,4-5,9-15H2,(H,25,28)/t18?,19-,20-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 498 | n/a | n/a | n/a | n/a | n/a | n/a |
Incyte Corporation
Curated by ChEMBL
| Assay Description Inhibition of MMP-9 |
Bioorg Med Chem Lett 19: 5037-42 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S |
More data for this Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50301104
((5S,6S)-5-(hydroxycarbamoyl)-6-(4-phenyl-1,2,3,6-t...)Show SMILES ONC(=O)[C@H]1CC(CN[C@@H]1C(=O)N1CCC(=CC1)c1ccccc1)OC(=O)N1CCCC1 |r,c:16| Show InChI InChI=1S/C23H30N4O5/c28-21(25-31)19-14-18(32-23(30)27-10-4-5-11-27)15-24-20(19)22(29)26-12-8-17(9-13-26)16-6-2-1-3-7-16/h1-3,6-8,18-20,24,31H,4-5,9-15H2,(H,25,28)/t18?,19-,20-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Incyte Corporation
Curated by ChEMBL
| Assay Description Inhibition of MMP-3 |
Bioorg Med Chem Lett 19: 5037-42 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S |
More data for this Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50301104
((5S,6S)-5-(hydroxycarbamoyl)-6-(4-phenyl-1,2,3,6-t...)Show SMILES ONC(=O)[C@H]1CC(CN[C@@H]1C(=O)N1CCC(=CC1)c1ccccc1)OC(=O)N1CCCC1 |r,c:16| Show InChI InChI=1S/C23H30N4O5/c28-21(25-31)19-14-18(32-23(30)27-10-4-5-11-27)15-24-20(19)22(29)26-12-8-17(9-13-26)16-6-2-1-3-7-16/h1-3,6-8,18-20,24,31H,4-5,9-15H2,(H,25,28)/t18?,19-,20-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Incyte Corporation
Curated by ChEMBL
| Assay Description Inhibition of MMP-1 |
Bioorg Med Chem Lett 19: 5037-42 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S |
More data for this Ligand-Target Pair | |