Found 6 hits of ic50 for monomerid = 50310801 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Bifunctional epoxide hydrolase 2
(Homo sapiens (Human)) | BDBM50310801
(3-(3-amino-3-oxopropyl)-N-(4-chlorophenyl)-3-pheny...)Show SMILES NC(=O)CCC1(CCCN(C1)C(=O)Nc1ccc(Cl)cc1)c1ccccc1 Show InChI InChI=1S/C21H24ClN3O2/c22-17-7-9-18(10-8-17)24-20(27)25-14-4-12-21(15-25,13-11-19(23)26)16-5-2-1-3-6-16/h1-3,5-10H,4,11-15H2,(H2,23,26)(H,24,27) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human soluble epoxide hydrolase |
Bioorg Med Chem Lett 19: 5314-20 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.138
BindingDB Entry DOI: 10.7270/Q2S75GFP |
More data for this
Ligand-Target Pair | |
Bifunctional epoxide hydrolase 2
(Rattus norvegicus) | BDBM50310801
(3-(3-amino-3-oxopropyl)-N-(4-chlorophenyl)-3-pheny...)Show SMILES NC(=O)CCC1(CCCN(C1)C(=O)Nc1ccc(Cl)cc1)c1ccccc1 Show InChI InChI=1S/C21H24ClN3O2/c22-17-7-9-18(10-8-17)24-20(27)25-14-4-12-21(15-25,13-11-19(23)26)16-5-2-1-3-6-16/h1-3,5-10H,4,11-15H2,(H2,23,26)(H,24,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of rat soluble epoxide hydrolase |
Bioorg Med Chem Lett 19: 5314-20 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.138
BindingDB Entry DOI: 10.7270/Q2S75GFP |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50310801
(3-(3-amino-3-oxopropyl)-N-(4-chlorophenyl)-3-pheny...)Show SMILES NC(=O)CCC1(CCCN(C1)C(=O)Nc1ccc(Cl)cc1)c1ccccc1 Show InChI InChI=1S/C21H24ClN3O2/c22-17-7-9-18(10-8-17)24-20(27)25-14-4-12-21(15-25,13-11-19(23)26)16-5-2-1-3-6-16/h1-3,5-10H,4,11-15H2,(H2,23,26)(H,24,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of CYP3A4 |
Bioorg Med Chem Lett 19: 5314-20 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.138
BindingDB Entry DOI: 10.7270/Q2S75GFP |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50310801
(3-(3-amino-3-oxopropyl)-N-(4-chlorophenyl)-3-pheny...)Show SMILES NC(=O)CCC1(CCCN(C1)C(=O)Nc1ccc(Cl)cc1)c1ccccc1 Show InChI InChI=1S/C21H24ClN3O2/c22-17-7-9-18(10-8-17)24-20(27)25-14-4-12-21(15-25,13-11-19(23)26)16-5-2-1-3-6-16/h1-3,5-10H,4,11-15H2,(H2,23,26)(H,24,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of CYP2C9 |
Bioorg Med Chem Lett 19: 5314-20 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.138
BindingDB Entry DOI: 10.7270/Q2S75GFP |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50310801
(3-(3-amino-3-oxopropyl)-N-(4-chlorophenyl)-3-pheny...)Show SMILES NC(=O)CCC1(CCCN(C1)C(=O)Nc1ccc(Cl)cc1)c1ccccc1 Show InChI InChI=1S/C21H24ClN3O2/c22-17-7-9-18(10-8-17)24-20(27)25-14-4-12-21(15-25,13-11-19(23)26)16-5-2-1-3-6-16/h1-3,5-10H,4,11-15H2,(H2,23,26)(H,24,27) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of CYP2D6 |
Bioorg Med Chem Lett 19: 5314-20 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.138
BindingDB Entry DOI: 10.7270/Q2S75GFP |
More data for this
Ligand-Target Pair | |
Epoxide hydrolase 1
(Homo sapiens (Human)) | BDBM50310801
(3-(3-amino-3-oxopropyl)-N-(4-chlorophenyl)-3-pheny...)Show SMILES NC(=O)CCC1(CCCN(C1)C(=O)Nc1ccc(Cl)cc1)c1ccccc1 Show InChI InChI=1S/C21H24ClN3O2/c22-17-7-9-18(10-8-17)24-20(27)25-14-4-12-21(15-25,13-11-19(23)26)16-5-2-1-3-6-16/h1-3,5-10H,4,11-15H2,(H2,23,26)(H,24,27) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human microsomal epoxide hydrolase |
Bioorg Med Chem Lett 19: 5314-20 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.138
BindingDB Entry DOI: 10.7270/Q2S75GFP |
More data for this
Ligand-Target Pair | |
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