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Compile Data Set for Download or QSAR

Found 9 hits of ic50 for monomerid = 50313569   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein kinase C theta type


(Homo sapiens (Human))
BDBM50313569
PNG
((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...)
Show SMILES CN1CCN(Cc2cccc(\C=C\c3cncc(C#N)c3Nc3ccc4[nH]ccc4c3C)n2)CC1
Show InChI InChI=1S/C28H29N7/c1-20-25-10-11-31-27(25)9-8-26(20)33-28-21(17-30-18-22(28)16-29)6-7-23-4-3-5-24(32-23)19-35-14-12-34(2)13-15-35/h3-11,17-18,31H,12-15,19H2,1-2H3,(H,30,33)/b7-6+
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n/an/a 1.10n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of PKCtheta


Bioorg Med Chem Lett 20: 1965-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.119
BindingDB Entry DOI: 10.7270/Q2H70FX5
More data for this
Ligand-Target Pair
Protein kinase C epsilon type


(Homo sapiens (Human))
BDBM50313569
PNG
((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...)
Show SMILES CN1CCN(Cc2cccc(\C=C\c3cncc(C#N)c3Nc3ccc4[nH]ccc4c3C)n2)CC1
Show InChI InChI=1S/C28H29N7/c1-20-25-10-11-31-27(25)9-8-26(20)33-28-21(17-30-18-22(28)16-29)6-7-23-4-3-5-24(32-23)19-35-14-12-34(2)13-15-35/h3-11,17-18,31H,12-15,19H2,1-2H3,(H,30,33)/b7-6+
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n/an/a 2n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of PKCepsilon


Bioorg Med Chem Lett 20: 1965-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.119
BindingDB Entry DOI: 10.7270/Q2H70FX5
More data for this
Ligand-Target Pair
Protein kinase C delta type


(Homo sapiens (Human))
BDBM50313569
PNG
((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...)
Show SMILES CN1CCN(Cc2cccc(\C=C\c3cncc(C#N)c3Nc3ccc4[nH]ccc4c3C)n2)CC1
Show InChI InChI=1S/C28H29N7/c1-20-25-10-11-31-27(25)9-8-26(20)33-28-21(17-30-18-22(28)16-29)6-7-23-4-3-5-24(32-23)19-35-14-12-34(2)13-15-35/h3-11,17-18,31H,12-15,19H2,1-2H3,(H,30,33)/b7-6+
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n/an/a 29n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of PKCdelta


Bioorg Med Chem Lett 20: 1965-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.119
BindingDB Entry DOI: 10.7270/Q2H70FX5
More data for this
Ligand-Target Pair
Protein kinase C eta type


(Homo sapiens (Human))
BDBM50313569
PNG
((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...)
Show SMILES CN1CCN(Cc2cccc(\C=C\c3cncc(C#N)c3Nc3ccc4[nH]ccc4c3C)n2)CC1
Show InChI InChI=1S/C28H29N7/c1-20-25-10-11-31-27(25)9-8-26(20)33-28-21(17-30-18-22(28)16-29)6-7-23-4-3-5-24(32-23)19-35-14-12-34(2)13-15-35/h3-11,17-18,31H,12-15,19H2,1-2H3,(H,30,33)/b7-6+
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n/an/a 120n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of PKCeta


Bioorg Med Chem Lett 20: 1965-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.119
BindingDB Entry DOI: 10.7270/Q2H70FX5
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50313569
PNG
((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...)
Show SMILES CN1CCN(Cc2cccc(\C=C\c3cncc(C#N)c3Nc3ccc4[nH]ccc4c3C)n2)CC1
Show InChI InChI=1S/C28H29N7/c1-20-25-10-11-31-27(25)9-8-26(20)33-28-21(17-30-18-22(28)16-29)6-7-23-4-3-5-24(32-23)19-35-14-12-34(2)13-15-35/h3-11,17-18,31H,12-15,19H2,1-2H3,(H,30,33)/b7-6+
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n/an/a 130n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of Src


Bioorg Med Chem Lett 20: 1965-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.119
BindingDB Entry DOI: 10.7270/Q2H70FX5
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lyn


(Homo sapiens (Human))
BDBM50313569
PNG
((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...)
Show SMILES CN1CCN(Cc2cccc(\C=C\c3cncc(C#N)c3Nc3ccc4[nH]ccc4c3C)n2)CC1
Show InChI InChI=1S/C28H29N7/c1-20-25-10-11-31-27(25)9-8-26(20)33-28-21(17-30-18-22(28)16-29)6-7-23-4-3-5-24(32-23)19-35-14-12-34(2)13-15-35/h3-11,17-18,31H,12-15,19H2,1-2H3,(H,30,33)/b7-6+
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n/an/a 540n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of Lyn


Bioorg Med Chem Lett 20: 1965-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.119
BindingDB Entry DOI: 10.7270/Q2H70FX5
More data for this
Ligand-Target Pair
Protein kinase C beta type


(Homo sapiens (Human))
BDBM50313569
PNG
((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...)
Show SMILES CN1CCN(Cc2cccc(\C=C\c3cncc(C#N)c3Nc3ccc4[nH]ccc4c3C)n2)CC1
Show InChI InChI=1S/C28H29N7/c1-20-25-10-11-31-27(25)9-8-26(20)33-28-21(17-30-18-22(28)16-29)6-7-23-4-3-5-24(32-23)19-35-14-12-34(2)13-15-35/h3-11,17-18,31H,12-15,19H2,1-2H3,(H,30,33)/b7-6+
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n/an/a 700n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of PKCbeta


Bioorg Med Chem Lett 20: 1965-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.119
BindingDB Entry DOI: 10.7270/Q2H70FX5
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50313569
PNG
((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...)
Show SMILES CN1CCN(Cc2cccc(\C=C\c3cncc(C#N)c3Nc3ccc4[nH]ccc4c3C)n2)CC1
Show InChI InChI=1S/C28H29N7/c1-20-25-10-11-31-27(25)9-8-26(20)33-28-21(17-30-18-22(28)16-29)6-7-23-4-3-5-24(32-23)19-35-14-12-34(2)13-15-35/h3-11,17-18,31H,12-15,19H2,1-2H3,(H,30,33)/b7-6+
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n/an/a 790n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of LCK


Bioorg Med Chem Lett 20: 1965-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.119
BindingDB Entry DOI: 10.7270/Q2H70FX5
More data for this
Ligand-Target Pair
Protein kinase C zeta type


(Homo sapiens (Human))
BDBM50313569
PNG
((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...)
Show SMILES CN1CCN(Cc2cccc(\C=C\c3cncc(C#N)c3Nc3ccc4[nH]ccc4c3C)n2)CC1
Show InChI InChI=1S/C28H29N7/c1-20-25-10-11-31-27(25)9-8-26(20)33-28-21(17-30-18-22(28)16-29)6-7-23-4-3-5-24(32-23)19-35-14-12-34(2)13-15-35/h3-11,17-18,31H,12-15,19H2,1-2H3,(H,30,33)/b7-6+
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n/an/a>1.00E+5n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of PKCzeta


Bioorg Med Chem Lett 20: 1965-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.119
BindingDB Entry DOI: 10.7270/Q2H70FX5
More data for this
Ligand-Target Pair