BindingDB PrimarySearch

Found 6 hits of ic50 for monomerid = 50314388
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Substance-P receptor (Homo sapiens (Human))	BDBM50314388 ((1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 2354-8 (2010) Article DOI: 10.1016/j.bmcl.2010.01.120 BindingDB Entry DOI: 10.7270/Q2JD4XR8
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50314388 ((1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in presence of 50% human serum				Bioorg Med Chem Lett 20: 2354-8 (2010) Article DOI: 10.1016/j.bmcl.2010.01.120 BindingDB Entry DOI: 10.7270/Q2JD4XR8
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 2 (Homo sapiens (Human))	BDBM50314388 ((1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Induction of human PXR				Bioorg Med Chem Lett 20: 2354-8 (2010) Article DOI: 10.1016/j.bmcl.2010.01.120 BindingDB Entry DOI: 10.7270/Q2JD4XR8
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50314388 ((1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of CYP2D6				Bioorg Med Chem Lett 20: 2354-8 (2010) Article DOI: 10.1016/j.bmcl.2010.01.120 BindingDB Entry DOI: 10.7270/Q2JD4XR8
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50314388 ((1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of CYP2C9				Bioorg Med Chem Lett 20: 2354-8 (2010) Article DOI: 10.1016/j.bmcl.2010.01.120 BindingDB Entry DOI: 10.7270/Q2JD4XR8
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50314388 ((1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of CYP3A4				Bioorg Med Chem Lett 20: 2354-8 (2010) Article DOI: 10.1016/j.bmcl.2010.01.120 BindingDB Entry DOI: 10.7270/Q2JD4XR8
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair