Found 6 hits of ic50 for monomerid = 50315467 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50315467
(CHEMBL1093791 | N-(4-fluorophenylsulfonyl)-3-(3-hy...)Show SMILES OC1C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C28H21FN2O5S/c29-22-11-13-23(14-12-22)37(35,36)30-25(32)15-10-20-6-3-7-24-26(20)31(28(34)27(24)33)17-18-8-9-19-4-1-2-5-21(19)16-18/h1-16,27,33H,17H2,(H,30,32)/b15-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer |
Bioorg Med Chem Lett 20: 2658-64 (2010)
Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50315467
(CHEMBL1093791 | N-(4-fluorophenylsulfonyl)-3-(3-hy...)Show SMILES OC1C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C28H21FN2O5S/c29-22-11-13-23(14-12-22)37(35,36)30-25(32)15-10-20-6-3-7-24-26(20)31(28(34)27(24)33)17-18-8-9-19-4-1-2-5-21(19)16-18/h1-16,27,33H,17H2,(H,30,32)/b15-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 19.4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum |
Bioorg Med Chem Lett 20: 2658-64 (2010)
Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50315467
(CHEMBL1093791 | N-(4-fluorophenylsulfonyl)-3-(3-hy...)Show SMILES OC1C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C28H21FN2O5S/c29-22-11-13-23(14-12-22)37(35,36)30-25(32)15-10-20-6-3-7-24-26(20)31(28(34)27(24)33)17-18-8-9-19-4-1-2-5-21(19)16-18/h1-16,27,33H,17H2,(H,30,32)/b15-10+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Binding affinity to human EP4 receptor by radioligand displacement assay |
Bioorg Med Chem Lett 20: 2658-64 (2010)
Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG |
More data for this Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50315467
(CHEMBL1093791 | N-(4-fluorophenylsulfonyl)-3-(3-hy...)Show SMILES OC1C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C28H21FN2O5S/c29-22-11-13-23(14-12-22)37(35,36)30-25(32)15-10-20-6-3-7-24-26(20)31(28(34)27(24)33)17-18-8-9-19-4-1-2-5-21(19)16-18/h1-16,27,33H,17H2,(H,30,32)/b15-10+ | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Binding affinity to human IP receptor by radioligand displacement assay |
Bioorg Med Chem Lett 20: 2658-64 (2010)
Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50315467
(CHEMBL1093791 | N-(4-fluorophenylsulfonyl)-3-(3-hy...)Show SMILES OC1C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C28H21FN2O5S/c29-22-11-13-23(14-12-22)37(35,36)30-25(32)15-10-20-6-3-7-24-26(20)31(28(34)27(24)33)17-18-8-9-19-4-1-2-5-21(19)16-18/h1-16,27,33H,17H2,(H,30,32)/b15-10+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Binding affinity to human EP2 receptor by radioligand displacement assay |
Bioorg Med Chem Lett 20: 2658-64 (2010)
Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG |
More data for this Ligand-Target Pair | |
Prostaglandin F2-alpha receptor
(Homo sapiens (Human)) | BDBM50315467
(CHEMBL1093791 | N-(4-fluorophenylsulfonyl)-3-(3-hy...)Show SMILES OC1C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C28H21FN2O5S/c29-22-11-13-23(14-12-22)37(35,36)30-25(32)15-10-20-6-3-7-24-26(20)31(28(34)27(24)33)17-18-8-9-19-4-1-2-5-21(19)16-18/h1-16,27,33H,17H2,(H,30,32)/b15-10+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Binding affinity to human FP receptor by radioligand displacement assay |
Bioorg Med Chem Lett 20: 2658-64 (2010)
Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG |
More data for this Ligand-Target Pair | |