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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50318141   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))		BDBM50318141
PNG
(3-ethyl-N-(6-methylpyridin-2-yl)-5-(piperazin-1-yl...)
Show SMILES CCc1nn(CCOCC(F)(F)F)c2c(Nc3cccc(C)n3)nc(nc12)N1CCNCC1
Show InChI InChI=1S/C21H27F3N8O/c1-3-15-17-18(32(30-15)11-12-33-13-21(22,23)24)19(27-16-6-4-5-14(2)26-16)29-20(28-17)31-9-7-25-8-10-31/h4-6,25H,3,7-13H2,1-2H3,(H,26,27,28,29)
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n/an/a 1n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of PDE5

Bioorg Med Chem Lett 20: 3125-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.03.106
BindingDB Entry DOI: 10.7270/Q2WH2QXD
More data for this
Ligand-Target Pair