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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50326186   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA topoisomerase 1


(Homo sapiens (Human))		BDBM50326186
PNG
((E)-9-Methoxy-11H-indeno[1,2-c]quinolin-11-one O-2...)
Show SMILES COc1ccc-2c(c1)\C(=N/OCCN1CCCC1)c1c-2cnc2ccccc12
Show InChI InChI=1S/C23H23N3O2/c1-27-16-8-9-17-19(14-16)23(25-28-13-12-26-10-4-5-11-26)22-18-6-2-3-7-21(18)24-15-20(17)22/h2-3,6-9,14-15H,4-5,10-13H2,1H3/b25-23+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 8.20E+3n/an/an/an/an/an/a



Kaohsiung Medical University

Curated by ChEMBL


Assay Description
Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresis

J Med Chem 53: 6164-79 (2010)


Article DOI: 10.1021/jm1005447
BindingDB Entry DOI: 10.7270/Q2BZ6710
More data for this
Ligand-Target Pair