Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Non-specific protein-tyrosine kinase (Homo sapiens (Human)) | BDBM50328136 (6-(1H-pyrazol-4-yl)-N-(4-(trifluoromethoxy)phenyl)...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 90 | n/a | n/a | n/a | n/a | 7.5 | n/a |
DANA-FARBER CANCER INSTITUTE, INC.; THE SCRIPPS RESEARCH INSTITUTE US Patent | Assay Description In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im... | US Patent US9670214 (2017) BindingDB Entry DOI: 10.7270/Q2000086 | |||||||||||
More data for this Ligand-Target Pair |