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Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 50329216   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type 10 subunit alpha


(Homo sapiens (Human))
BDBM50329216
PNG
(CHEMBL1271205 | N-(3,5-dimethylphenyl)-6-(4-(trifl...)
Show SMILES Cc1cc(C)cc(NC(=O)c2cccc(n2)-c2ccc(OC(F)(F)F)cc2)c1
Show InChI InChI=1S/C21H17F3N2O2/c1-13-10-14(2)12-16(11-13)25-20(27)19-5-3-4-18(26-19)15-6-8-17(9-7-15)28-21(22,23)24/h3-12H,1-2H3,(H,25,27)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 64n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human NaV1.8 by electrophysiology


Bioorg Med Chem Lett 20: 6812-5 (2010)


Article DOI: 10.1016/j.bmcl.2010.08.121
BindingDB Entry DOI: 10.7270/Q2F76CS6
More data for this
Ligand-Target Pair
Sodium channel protein type 10 subunit alpha


(Rattus norvegicus (Rat))
BDBM50329216
PNG
(CHEMBL1271205 | N-(3,5-dimethylphenyl)-6-(4-(trifl...)
Show SMILES Cc1cc(C)cc(NC(=O)c2cccc(n2)-c2ccc(OC(F)(F)F)cc2)c1
Show InChI InChI=1S/C21H17F3N2O2/c1-13-10-14(2)12-16(11-13)25-20(27)19-5-3-4-18(26-19)15-6-8-17(9-7-15)28-21(22,23)24/h3-12H,1-2H3,(H,25,27)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 510n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology


Bioorg Med Chem Lett 20: 6812-5 (2010)


Article DOI: 10.1016/j.bmcl.2010.08.121
BindingDB Entry DOI: 10.7270/Q2F76CS6
More data for this
Ligand-Target Pair
Sodium channel protein type 10 subunit alpha


(Mus musculus)
BDBM50329216
PNG
(CHEMBL1271205 | N-(3,5-dimethylphenyl)-6-(4-(trifl...)
Show SMILES Cc1cc(C)cc(NC(=O)c2cccc(n2)-c2ccc(OC(F)(F)F)cc2)c1
Show InChI InChI=1S/C21H17F3N2O2/c1-13-10-14(2)12-16(11-13)25-20(27)19-5-3-4-18(26-19)15-6-8-17(9-7-15)28-21(22,23)24/h3-12H,1-2H3,(H,25,27)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse NaV1.8 by electrophysiology


Bioorg Med Chem Lett 20: 6812-5 (2010)


Article DOI: 10.1016/j.bmcl.2010.08.121
BindingDB Entry DOI: 10.7270/Q2F76CS6
More data for this
Ligand-Target Pair