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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50330510   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50330510
PNG
(3-(2,6-Dichlorophenylsulfonyl)-5-(4-methylpiperazi...)
Show SMILES CN1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1c(Cl)cccc1Cl
Show InChI InChI=1S/C18H18Cl2N4O2S/c1-23-7-9-24(10-8-23)12-5-6-16-13(11-12)18(22-21-16)27(25,26)17-14(19)3-2-4-15(17)20/h2-6,11H,7-10H2,1H3,(H,21,22)
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Article
PubMed
n/an/a 40n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assay


J Med Chem 53: 7639-46 (2010)


Article DOI: 10.1021/jm1007825
BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
More data for this
Ligand-Target Pair