Found 7 hits of ic50 for monomerid = 50346799 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50346799
(CHEMBL1795858)Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1ccc(cc1)C(=O)c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C32H30N2O5S2/c1-2-3-7-23-10-12-24(13-11-23)16-19-28-20-21-30(40-28)41(38,39)34-29(32(36)33-37)22-25-14-17-27(18-15-25)31(35)26-8-5-4-6-9-26/h4-6,8-15,17-18,20-21,29,34,37H,2-3,7,22H2,1H3,(H,33,36)/t29-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of human MMP2 by fluorometric assay |
Eur J Med Chem 46: 2617-29 (2011)
Article DOI: 10.1016/j.ejmech.2011.03.033
BindingDB Entry DOI: 10.7270/Q2RN3864 |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50346799
(CHEMBL1795858)Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1ccc(cc1)C(=O)c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C32H30N2O5S2/c1-2-3-7-23-10-12-24(13-11-23)16-19-28-20-21-30(40-28)41(38,39)34-29(32(36)33-37)22-25-14-17-27(18-15-25)31(35)26-8-5-4-6-9-26/h4-6,8-15,17-18,20-21,29,34,37H,2-3,7,22H2,1H3,(H,33,36)/t29-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of human MMP9 by fluorometric assay |
Eur J Med Chem 46: 2617-29 (2011)
Article DOI: 10.1016/j.ejmech.2011.03.033
BindingDB Entry DOI: 10.7270/Q2RN3864 |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50346799
(CHEMBL1795858)Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1ccc(cc1)C(=O)c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C32H30N2O5S2/c1-2-3-7-23-10-12-24(13-11-23)16-19-28-20-21-30(40-28)41(38,39)34-29(32(36)33-37)22-25-14-17-27(18-15-25)31(35)26-8-5-4-6-9-26/h4-6,8-15,17-18,20-21,29,34,37H,2-3,7,22H2,1H3,(H,33,36)/t29-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 84 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of human MMP3 by fluorometric assay |
Eur J Med Chem 46: 2617-29 (2011)
Article DOI: 10.1016/j.ejmech.2011.03.033
BindingDB Entry DOI: 10.7270/Q2RN3864 |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-25
(Homo sapiens (Human)) | BDBM50346799
(CHEMBL1795858)Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1ccc(cc1)C(=O)c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C32H30N2O5S2/c1-2-3-7-23-10-12-24(13-11-23)16-19-28-20-21-30(40-28)41(38,39)34-29(32(36)33-37)22-25-14-17-27(18-15-25)31(35)26-8-5-4-6-9-26/h4-6,8-15,17-18,20-21,29,34,37H,2-3,7,22H2,1H3,(H,33,36)/t29-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of human MMP25 by fluorometric assay |
Eur J Med Chem 46: 2617-29 (2011)
Article DOI: 10.1016/j.ejmech.2011.03.033
BindingDB Entry DOI: 10.7270/Q2RN3864 |
More data for this
Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50346799
(CHEMBL1795858)Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1ccc(cc1)C(=O)c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C32H30N2O5S2/c1-2-3-7-23-10-12-24(13-11-23)16-19-28-20-21-30(40-28)41(38,39)34-29(32(36)33-37)22-25-14-17-27(18-15-25)31(35)26-8-5-4-6-9-26/h4-6,8-15,17-18,20-21,29,34,37H,2-3,7,22H2,1H3,(H,33,36)/t29-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of human MMP8 by fluorometric assay |
Eur J Med Chem 46: 2617-29 (2011)
Article DOI: 10.1016/j.ejmech.2011.03.033
BindingDB Entry DOI: 10.7270/Q2RN3864 |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-14
(Homo sapiens (Human)) | BDBM50346799
(CHEMBL1795858)Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1ccc(cc1)C(=O)c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C32H30N2O5S2/c1-2-3-7-23-10-12-24(13-11-23)16-19-28-20-21-30(40-28)41(38,39)34-29(32(36)33-37)22-25-14-17-27(18-15-25)31(35)26-8-5-4-6-9-26/h4-6,8-15,17-18,20-21,29,34,37H,2-3,7,22H2,1H3,(H,33,36)/t29-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of human MMP14 by fluorometric assay |
Eur J Med Chem 46: 2617-29 (2011)
Article DOI: 10.1016/j.ejmech.2011.03.033
BindingDB Entry DOI: 10.7270/Q2RN3864 |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50346799
(CHEMBL1795858)Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1ccc(cc1)C(=O)c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C32H30N2O5S2/c1-2-3-7-23-10-12-24(13-11-23)16-19-28-20-21-30(40-28)41(38,39)34-29(32(36)33-37)22-25-14-17-27(18-15-25)31(35)26-8-5-4-6-9-26/h4-6,8-15,17-18,20-21,29,34,37H,2-3,7,22H2,1H3,(H,33,36)/t29-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of human MMP1 by fluorometric assay |
Eur J Med Chem 46: 2617-29 (2011)
Article DOI: 10.1016/j.ejmech.2011.03.033
BindingDB Entry DOI: 10.7270/Q2RN3864 |
More data for this
Ligand-Target Pair | |
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