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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50376827   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C5a anaphylatoxin chemotactic receptor 1


(Homo sapiens (Human))		BDBM50376827
PNG
(CHEMBL411265)
Show SMILES CCN(C1CCCc2nc(cc(OC)c12)-c1c(Cl)cccc1OC)c1cccc2ccccc12 |w:3.2|
Show InChI InChI=1S/C29H29ClN2O2/c1-4-32(24-15-7-11-19-10-5-6-12-20(19)24)25-16-9-14-22-29(25)27(34-3)18-23(31-22)28-21(30)13-8-17-26(28)33-2/h5-8,10-13,15,17-18,25H,4,9,14,16H2,1-3H3
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Similars
Article
PubMed
n/an/a 110n/an/an/an/an/an/a



Johnson& Johnson PRD

Curated by ChEMBL


Assay Description
Antagonist activity at human C5a receptor in U937 cells assessed as inhibition of anaphylatoxin-induced intracellular calcium mobilization

Bioorg Med Chem Lett 18: 2544-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.03.049
BindingDB Entry DOI: 10.7270/Q2JM2BHD
More data for this
Ligand-Target Pair