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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50377339   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50377339
PNG
(CHEMBL404879)
Show SMILES CC1CC(C)(C)Nc2c(C)cc(c(Cl)c12)-c1ccc(Cl)c2cc[nH]c12 |w:1.0|
Show InChI InChI=1S/C21H22Cl2N2/c1-11-9-15(13-5-6-16(22)14-7-8-24-20(13)14)18(23)17-12(2)10-21(3,4)25-19(11)17/h5-9,12,24-25H,10H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 12n/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at glucocorticoid receptor assessed as inhibition of dexamethasone-induced glucose response element transcriptional transactivati...


Bioorg Med Chem Lett 18: 3504-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.029
BindingDB Entry DOI: 10.7270/Q2CR5V8F
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50377339
PNG
(CHEMBL404879)
Show SMILES CC1CC(C)(C)Nc2c(C)cc(c(Cl)c12)-c1ccc(Cl)c2cc[nH]c12 |w:1.0|
Show InChI InChI=1S/C21H22Cl2N2/c1-11-9-15(13-5-6-16(22)14-7-8-24-20(13)14)18(23)17-12(2)10-21(3,4)25-19(11)17/h5-9,12,24-25H,10H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Activity at glucocorticoid receptor assessed as repression of TNFalpha and IL1 beta-induced E-selectin expression


Bioorg Med Chem Lett 18: 3504-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.029
BindingDB Entry DOI: 10.7270/Q2CR5V8F
More data for this
Ligand-Target Pair