BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50392471   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neutral ceramidase


(Homo sapiens (Human))		BDBM50392471
PNG
(CHEMBL2152040)
Show SMILES CCCCCCCCCCCCS(=O)(=O)N[C@H](CO)[C@H](O)c1ccc(cc1)[N+]([O-])=O |r|
Show InChI InChI=1S/C21H36N2O6S/c1-2-3-4-5-6-7-8-9-10-11-16-30(28,29)22-20(17-24)21(25)18-12-14-19(15-13-18)23(26)27/h12-15,20-22,24-25H,2-11,16-17H2,1H3/t20-,21-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.40E+4n/an/an/an/an/an/a



Humboldt Universit£t zu Berlin

Curated by ChEMBL


Assay Description
Inhibition of recombinant human nCDase expressed in Sf9 cells using fluorescently-labeled acyl-NBD-C12-ceramide as substrate after 2 hrs by fluoresce...

Bioorg Med Chem 20: 6162-70 (2012)


Article DOI: 10.1016/j.bmc.2012.08.031
BindingDB Entry DOI: 10.7270/Q29Z960Z
More data for this
Ligand-Target Pair