Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Stromelysin-3 (Mus musculus) | BDBM50404889 (CHEMBL303714) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 0.0280 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre Curated by ChEMBL | Assay Description Cytotoxicity against human NB-1 cells by MTT assay | Bioorg Med Chem Lett 19: 2420-8 (2009) Article DOI: 10.1016/j.bmcl.2009.03.069 BindingDB Entry DOI: 10.7270/Q2W098R8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50404889 (CHEMBL303714) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre Curated by ChEMBL | Assay Description Inhibition of recombinant HIV1 reverse transcriptase in cell free Quan-T-RT by scintillation proximity assay | Bioorg Med Chem Lett 19: 2420-8 (2009) Article DOI: 10.1016/j.bmcl.2009.03.069 BindingDB Entry DOI: 10.7270/Q2W098R8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Membrane primary amine oxidase (Rattus norvegicus (Rat)) | BDBM50404889 (CHEMBL303714) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc. Curated by ChEMBL | Assay Description Inhibition of rat VAP-1 expressed in CHO cells using [14C]-benzylamine as substrate preincubated for 30 mins prior to substrate addition measured aft... | Bioorg Med Chem 21: 3873-81 (2013) Article DOI: 10.1016/j.bmc.2013.04.011 BindingDB Entry DOI: 10.7270/Q22B90DG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Membrane primary amine oxidase (Homo sapiens (Human)) | BDBM50404889 (CHEMBL303714) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc. Curated by ChEMBL | Assay Description Inhibition of human VAP-1 expressed in CHO cells using [14C]-benzylamine as substrate preincubated for 30 mins prior to substrate addition measured a... | Bioorg Med Chem 21: 3873-81 (2013) Article DOI: 10.1016/j.bmc.2013.04.011 BindingDB Entry DOI: 10.7270/Q22B90DG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2B1 (Rattus norvegicus) | BDBM50404889 (CHEMBL303714) | PDB UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 4.57E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats. | J Med Chem 25: 887-92 (1982) BindingDB Entry DOI: 10.7270/Q2VT1T8J | |||||||||||
More data for this Ligand-Target Pair |