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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50436703   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase A


(Homo sapiens (Human))		BDBM50436703
PNG
(CHEMBL2398651)
Show SMILES CNC(=O)Nc1ccc(CCNc2ncnc3oc(c(-c4ccccc4)c23)-c2ccccc2)cc1
Show InChI InChI=1S/C28H25N5O2/c1-29-28(34)33-22-14-12-19(13-15-22)16-17-30-26-24-23(20-8-4-2-5-9-20)25(21-10-6-3-7-11-21)35-27(24)32-18-31-26/h2-15,18H,16-17H2,1H3,(H2,29,33,34)(H,30,31,32)
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Article
PubMed
n/an/a 203n/an/an/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged Aurora kinase A catalytic domain (123 to 401 amino acids) (unknown origin) expressed in sf9 cells using tetra(LRRWSLG) as su...

J Med Chem 56: 5247-60 (2014)


Article DOI: 10.1021/jm4006059
BindingDB Entry DOI: 10.7270/Q2J104K6
More data for this
Ligand-Target Pair