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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50444135   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
G protein-coupled receptor kinase 5


(Homo sapiens (Human))		BDBM50444135
PNG
(CHEMBL3093260)
Show SMILES Nc1ncc(cc1-c1nc2cc(ccc2o1)N1CCCC1)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C24H27N7O/c25-23-20(24-29-21-12-19(3-4-22(21)32-24)30-9-1-2-10-30)11-16(13-27-23)17-14-28-31(15-17)18-5-7-26-8-6-18/h3-4,11-15,18,26H,1-2,5-10H2,(H2,25,27)
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n/an/a 120n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of GRK-5 (unknown origin) preincubated with enzyme for 10 mins before adding peptide substrate and ATP measured after 1 hr by LANCE-TR-FRE...

Bioorg Med Chem Lett 23: 6711-6 (2013)


Article DOI: 10.1016/j.bmcl.2013.10.036
BindingDB Entry DOI: 10.7270/Q2SX6FPP
More data for this
Ligand-Target Pair
Beta-adrenergic receptor kinase 1


(Homo sapiens (Human))		BDBM50444135
PNG
(CHEMBL3093260)
Show SMILES Nc1ncc(cc1-c1nc2cc(ccc2o1)N1CCCC1)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C24H27N7O/c25-23-20(24-29-21-12-19(3-4-22(21)32-24)30-9-1-2-10-30)11-16(13-27-23)17-14-28-31(15-17)18-5-7-26-8-6-18/h3-4,11-15,18,26H,1-2,5-10H2,(H2,25,27)
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n/an/a 1.65E+3n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of GRK-2 (unknown origin) preincubated with enzyme for 10 mins before adding peptide substrate and ATP measured after 1 hr by LANCE-TR-FRE...

Bioorg Med Chem Lett 23: 6711-6 (2013)


Article DOI: 10.1016/j.bmcl.2013.10.036
BindingDB Entry DOI: 10.7270/Q2SX6FPP
More data for this
Ligand-Target Pair