BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 7 hits of ic50 for monomerid = 50503387   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM50503387
PNG
(CHEMBL4475135)
Show SMILES Cc1cc(C)cc(Nc2nccc(n2)-c2c(nnn2C2CCNCC2)-c2ccc(F)cc2)c1
Show InChI InChI=1S/C25H26FN7/c1-16-13-17(2)15-20(14-16)29-25-28-12-9-22(30-25)24-23(18-3-5-19(26)6-4-18)31-32-33(24)21-7-10-27-11-8-21/h3-6,9,12-15,21,27H,7-8,10-11H2,1-2H3,(H,28,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.70E+4n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Inhibition of BRD4 N-terminal bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3) by alpha-screen assay


J Med Chem 61: 9316-9334 (2018)


Article DOI: 10.1021/acs.jmedchem.8b01248
BindingDB Entry DOI: 10.7270/Q25T3PRQ
More data for this
Ligand-Target Pair
Bromodomain-containing protein 2


(Homo sapiens (Human))
BDBM50503387
PNG
(CHEMBL4475135)
Show SMILES Cc1cc(C)cc(Nc2nccc(n2)-c2c(nnn2C2CCNCC2)-c2ccc(F)cc2)c1
Show InChI InChI=1S/C25H26FN7/c1-16-13-17(2)15-20(14-16)29-25-28-12-9-22(30-25)24-23(18-3-5-19(26)6-4-18)31-32-33(24)21-7-10-27-11-8-21/h3-6,9,12-15,21,27H,7-8,10-11H2,1-2H3,(H,28,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.00E+4n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Inhibition of BRD2 C-terminal bromodomain 2 (unknown origin) expressed in Escherichia coli Bl21(DE3) by alpha-screen assay


J Med Chem 61: 9316-9334 (2018)


Article DOI: 10.1021/acs.jmedchem.8b01248
BindingDB Entry DOI: 10.7270/Q25T3PRQ
More data for this
Ligand-Target Pair
Bromodomain testis-specific protein


(Homo sapiens (Human))
BDBM50503387
PNG
(CHEMBL4475135)
Show SMILES Cc1cc(C)cc(Nc2nccc(n2)-c2c(nnn2C2CCNCC2)-c2ccc(F)cc2)c1
Show InChI InChI=1S/C25H26FN7/c1-16-13-17(2)15-20(14-16)29-25-28-12-9-22(30-25)24-23(18-3-5-19(26)6-4-18)31-32-33(24)21-7-10-27-11-8-21/h3-6,9,12-15,21,27H,7-8,10-11H2,1-2H3,(H,28,29,30)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.60E+4n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Inhibition of BRDT N-terminal bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3) by alpha-screen assay


J Med Chem 61: 9316-9334 (2018)


Article DOI: 10.1021/acs.jmedchem.8b01248
BindingDB Entry DOI: 10.7270/Q25T3PRQ
More data for this
Ligand-Target Pair
Bromodomain-containing protein 2


(Homo sapiens (Human))
BDBM50503387
PNG
(CHEMBL4475135)
Show SMILES Cc1cc(C)cc(Nc2nccc(n2)-c2c(nnn2C2CCNCC2)-c2ccc(F)cc2)c1
Show InChI InChI=1S/C25H26FN7/c1-16-13-17(2)15-20(14-16)29-25-28-12-9-22(30-25)24-23(18-3-5-19(26)6-4-18)31-32-33(24)21-7-10-27-11-8-21/h3-6,9,12-15,21,27H,7-8,10-11H2,1-2H3,(H,28,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.30E+4n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Inhibition of BRD2 N-terminal bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3) by alpha-screen assay


J Med Chem 61: 9316-9334 (2018)


Article DOI: 10.1021/acs.jmedchem.8b01248
BindingDB Entry DOI: 10.7270/Q25T3PRQ
More data for this
Ligand-Target Pair
Bromodomain-containing protein 3


(Homo sapiens (Human))
BDBM50503387
PNG
(CHEMBL4475135)
Show SMILES Cc1cc(C)cc(Nc2nccc(n2)-c2c(nnn2C2CCNCC2)-c2ccc(F)cc2)c1
Show InChI InChI=1S/C25H26FN7/c1-16-13-17(2)15-20(14-16)29-25-28-12-9-22(30-25)24-23(18-3-5-19(26)6-4-18)31-32-33(24)21-7-10-27-11-8-21/h3-6,9,12-15,21,27H,7-8,10-11H2,1-2H3,(H,28,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.10E+4n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Inhibition of BRD3 N-terminal bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3) by alpha-screen assay


J Med Chem 61: 9316-9334 (2018)


Article DOI: 10.1021/acs.jmedchem.8b01248
BindingDB Entry DOI: 10.7270/Q25T3PRQ
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM50503387
PNG
(CHEMBL4475135)
Show SMILES Cc1cc(C)cc(Nc2nccc(n2)-c2c(nnn2C2CCNCC2)-c2ccc(F)cc2)c1
Show InChI InChI=1S/C25H26FN7/c1-16-13-17(2)15-20(14-16)29-25-28-12-9-22(30-25)24-23(18-3-5-19(26)6-4-18)31-32-33(24)21-7-10-27-11-8-21/h3-6,9,12-15,21,27H,7-8,10-11H2,1-2H3,(H,28,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.50E+4n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Inhibition of BRD4 C-terminal bromodomain 2 (unknown origin) expressed in Escherichia coli Bl21(DE3) by alpha-screen assay


J Med Chem 61: 9316-9334 (2018)


Article DOI: 10.1021/acs.jmedchem.8b01248
BindingDB Entry DOI: 10.7270/Q25T3PRQ
More data for this
Ligand-Target Pair
Bromodomain-containing protein 3


(Homo sapiens (Human))
BDBM50503387
PNG
(CHEMBL4475135)
Show SMILES Cc1cc(C)cc(Nc2nccc(n2)-c2c(nnn2C2CCNCC2)-c2ccc(F)cc2)c1
Show InChI InChI=1S/C25H26FN7/c1-16-13-17(2)15-20(14-16)29-25-28-12-9-22(30-25)24-23(18-3-5-19(26)6-4-18)31-32-33(24)21-7-10-27-11-8-21/h3-6,9,12-15,21,27H,7-8,10-11H2,1-2H3,(H,28,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.10E+5n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Inhibition of BRD3 C-terminal bromodomain 2 (unknown origin) expressed in Escherichia coli Bl21(DE3) by alpha-screen assay


J Med Chem 61: 9316-9334 (2018)


Article DOI: 10.1021/acs.jmedchem.8b01248
BindingDB Entry DOI: 10.7270/Q25T3PRQ
More data for this
Ligand-Target Pair