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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50533525   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Presenilin-1


(Homo sapiens (Human))
BDBM50533525
PNG
(CHEMBL4551156)
Show SMILES CC(C)n1nc2CCCc2c1Nc1nc(cs1)-c1ccc(c(F)c1)-n1cnc(C)c1
Show InChI InChI=1S/C22H23FN6S/c1-13(2)29-21(16-5-4-6-18(16)27-29)26-22-25-19(11-30-22)15-7-8-20(17(23)9-15)28-10-14(3)24-12-28/h7-13H,4-6H2,1-3H3,(H,25,26)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 66n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Modulation of gamma-secretase in human SH-SY5Y cells overexpressing wild-type human APP751 assessed as inhibition of Abeta42 level after 24 hrs by EL...


Bioorg Med Chem Lett 26: 3928-37 (2016)


Article DOI: 10.1016/j.bmcl.2016.07.011
BindingDB Entry DOI: 10.7270/Q2K077SR
More data for this
Ligand-Target Pair