Compile Data Set for Download or QSAR

Found 4 hits of ic50 for monomerid = 50535114   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50535114 (CHEMBL4583779) Show SMILES CN(C)c1ccc(cn1)-c1cc2nccnc2c(OC[C@@H]2CCCNC2)n1 |r| Show InChI InChI=1S/C20H24N6O/c1-26(2)18-6-5-15(12-24-18)16-10-17-19(23-9-8-22-17)20(25-16)27-13-14-4-3-7-21-11-14/h5-6,8-10,12,14,21H,3-4,7,11,13H2,1-2H3/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...				Bioorg Med Chem Lett 26: 4606-4612 (2016) Article DOI: 10.1016/j.bmcl.2016.08.070 BindingDB Entry DOI: 10.7270/Q2GM8BT3
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50535114 (CHEMBL4583779) Show SMILES CN(C)c1ccc(cn1)-c1cc2nccnc2c(OC[C@@H]2CCCNC2)n1 |r| Show InChI InChI=1S/C20H24N6O/c1-26(2)18-6-5-15(12-24-18)16-10-17-19(23-9-8-22-17)20(25-16)27-13-14-4-3-7-21-11-14/h5-6,8-10,12,14,21H,3-4,7,11,13H2,1-2H3/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of N-terminal-6His-tagged full length human Aurora B expressed in baculovirus using 5FAM-PKA-tide as substrate after 120 mins by fluoresce...				Bioorg Med Chem Lett 26: 4606-4612 (2016) Article DOI: 10.1016/j.bmcl.2016.08.070 BindingDB Entry DOI: 10.7270/Q2GM8BT3
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50535114 (CHEMBL4583779) Show SMILES CN(C)c1ccc(cn1)-c1cc2nccnc2c(OC[C@@H]2CCCNC2)n1 |r| Show InChI InChI=1S/C20H24N6O/c1-26(2)18-6-5-15(12-24-18)16-10-17-19(23-9-8-22-17)20(25-16)27-13-14-4-3-7-21-11-14/h5-6,8-10,12,14,21H,3-4,7,11,13H2,1-2H3/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of SYK in human B cells assessed as suppression of anti-IgM-induced CD69 surface expression preincubated for 30 mins followed by anti-IgM ...				Bioorg Med Chem Lett 26: 4606-4612 (2016) Article DOI: 10.1016/j.bmcl.2016.08.070 BindingDB Entry DOI: 10.7270/Q2GM8BT3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50535114 (CHEMBL4583779) Show SMILES CN(C)c1ccc(cn1)-c1cc2nccnc2c(OC[C@@H]2CCCNC2)n1 |r| Show InChI InChI=1S/C20H24N6O/c1-26(2)18-6-5-15(12-24-18)16-10-17-19(23-9-8-22-17)20(25-16)27-13-14-4-3-7-21-11-14/h5-6,8-10,12,14,21H,3-4,7,11,13H2,1-2H3/t14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of human ERG expressed in CHOK1 cell membranes after 2 hrs by cy3b-dofetilide-based fluorescence polarization assay				Bioorg Med Chem Lett 26: 4606-4612 (2016) Article DOI: 10.1016/j.bmcl.2016.08.070 BindingDB Entry DOI: 10.7270/Q2GM8BT3
					More data for this Ligand-Target Pair