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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 6240   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C]


(Homo sapiens (Human))		BDBM6240
PNG
(8-Ethyl-2-(4-pyrrol-1-ylphenylamino)-8H-pyrido[2,3...)
Show SMILES CCn1c2nc(Nc3ccc(cc3)-n3cccc3)ncc2ccc1=O
Show InChI InChI=1S/C19H17N5O/c1-2-24-17(25)10-5-14-13-20-19(22-18(14)24)21-15-6-8-16(9-7-15)23-11-3-4-12-23/h3-13H,2H2,1H3,(H,20,21,22)
PDB
MMDB

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Article
PubMed
n/an/a 2.75E+3n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research



Assay Description
The enzyme was assayed with substrate GST- retinoblastoma in the presence of 25 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...

J Med Chem 43: 4606-16 (2000)


Article DOI: 10.1021/jm000271k
BindingDB Entry DOI: 10.7270/Q25B00N4
More data for this
Ligand-Target Pair