Compile Data Set for Download or QSAR

Found 4 hits of ic50 for monomerid = 70816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM70816 (US9546164, 4 | US9694002, 6) Show SMILES Fc1ccc(CN2CCC[C@H](C2)Oc2cc(F)c(cc2C2CC2)C(=O)NS(=O)(=O)N2CCC2)c(Cl)c1 |r| Show InChI InChI=1S/C25H28ClF2N3O4S/c26-22-11-18(27)7-6-17(22)14-30-8-1-3-19(15-30)35-24-13-23(28)21(12-20(24)16-4-5-16)25(32)29-36(33,34)31-9-2-10-31/h6-7,11-13,16,19H,1-5,8-10,14-15H2,(H,29,32)/t19-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	7.4	25
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent					Assay Description Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...				US Patent US9694002 (2017) BindingDB Entry DOI: 10.7270/Q24B2ZFG
					More data for this Ligand-Target Pair
Sodium channel protein type 1/10/11/2/3/4/5/8/9 subunit alpha (Homo sapiens (Human))	BDBM70816 (US9546164, 4 | US9694002, 6) Show SMILES Fc1ccc(CN2CCC[C@H](C2)Oc2cc(F)c(cc2C2CC2)C(=O)NS(=O)(=O)N2CCC2)c(Cl)c1 |r| Show InChI InChI=1S/C25H28ClF2N3O4S/c26-22-11-18(27)7-6-17(22)14-30-8-1-3-19(15-30)35-24-13-23(28)21(12-20(24)16-4-5-16)25(32)29-36(33,34)31-9-2-10-31/h6-7,11-13,16,19H,1-5,8-10,14-15H2,(H,29,32)/t19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	25
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent					Assay Description Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...				US Patent US9694002 (2017) BindingDB Entry DOI: 10.7270/Q24B2ZFG
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM70816 (US9546164, 4 | US9694002, 6) Show SMILES Fc1ccc(CN2CCC[C@H](C2)Oc2cc(F)c(cc2C2CC2)C(=O)NS(=O)(=O)N2CCC2)c(Cl)c1 |r| Show InChI InChI=1S/C25H28ClF2N3O4S/c26-22-11-18(27)7-6-17(22)14-30-8-1-3-19(15-30)35-24-13-23(28)21(12-20(24)16-4-5-16)25(32)29-36(33,34)31-9-2-10-31/h6-7,11-13,16,19H,1-5,8-10,14-15H2,(H,29,32)/t19-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	7.4	25
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent					Assay Description Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...				US Patent US9694002 (2017) BindingDB Entry DOI: 10.7270/Q24B2ZFG
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM70816 (US9546164, 4 | US9694002, 6) Show SMILES Fc1ccc(CN2CCC[C@H](C2)Oc2cc(F)c(cc2C2CC2)C(=O)NS(=O)(=O)N2CCC2)c(Cl)c1 |r| Show InChI InChI=1S/C25H28ClF2N3O4S/c26-22-11-18(27)7-6-17(22)14-30-8-1-3-19(15-30)35-24-13-23(28)21(12-20(24)16-4-5-16)25(32)29-36(33,34)31-9-2-10-31/h6-7,11-13,16,19H,1-5,8-10,14-15H2,(H,29,32)/t19-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	7.4	25
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent					Assay Description Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...				US Patent US9546164 (2017) BindingDB Entry DOI: 10.7270/Q2JD4ZS4
					More data for this Ligand-Target Pair