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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 71285   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type 5 subunit alpha


(Homo sapiens (Human))
BDBM71285
PNG
(US9546164, 361 | US9694002, 361)
Show SMILES CS(=O)(=O)NC(=O)c1cc(C2CC2)c(OCC2CCN(CC2)C(c2ccccc2Cl)c2ccccc2Cl)cc1F
Show InChI InChI=1S/C30H31Cl2FN2O4S/c1-40(37,38)34-30(36)24-16-23(20-10-11-20)28(17-27(24)33)39-18-19-12-14-35(15-13-19)29(21-6-2-4-8-25(21)31)22-7-3-5-9-26(22)32/h2-9,16-17,19-20,29H,10-15,18H2,1H3,(H,34,36)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/a7.425



GENENTECH, INC.; XENON PHARMACEUTICALS INC.

US Patent




US Patent US9546164 (2017)


BindingDB Entry DOI: 10.7270/Q2JD4ZS4
More data for this
Ligand-Target Pair
Sodium Channel Complex


(Homo sapiens (Human))
BDBM71285
PNG
(US9546164, 361 | US9694002, 361)
Show SMILES CS(=O)(=O)NC(=O)c1cc(C2CC2)c(OCC2CCN(CC2)C(c2ccccc2Cl)c2ccccc2Cl)cc1F
Show InChI InChI=1S/C30H31Cl2FN2O4S/c1-40(37,38)34-30(36)24-16-23(20-10-11-20)28(17-27(24)33)39-18-19-12-14-35(15-13-19)29(21-6-2-4-8-25(21)31)22-7-3-5-9-26(22)32/h2-9,16-17,19-20,29H,10-15,18H2,1H3,(H,34,36)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/a7.425



GENENTECH, INC.; XENON PHARMACEUTICALS INC.

US Patent


Assay Description
Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...


US Patent US9694002 (2017)


BindingDB Entry DOI: 10.7270/Q24B2ZFG
More data for this
Ligand-Target Pair