Compile Data Set for Download or QSAR

Found 4 hits of ic50 for monomerid = 98027   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM98027 (US10472367, Compound Formula I | US10919901, Compo...) Show SMILES C[C@@H](O)CNC(=O)c1ccc(cc1F)-c1cnc2ncc(Cc3ccc4ncccc4c3)n2n1 |r| Show InChI InChI=1S/C25H21FN6O2/c1-15(33)12-28-24(34)20-6-5-18(11-21(20)26)23-14-30-25-29-13-19(32(25)31-23)10-16-4-7-22-17(9-16)3-2-8-27-22/h2-9,11,13-15,33H,10,12H2,1H3,(H,28,34)/t15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.550	n/a	n/a	n/a	n/a	7.5	30
Incyte Corporation US Patent					Assay Description The compounds of the intervention were screened in vitro for their ability to inhibit c-Met kinase activity.				US Patent US8487096 (2013) BindingDB Entry DOI: 10.7270/Q2319THZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM98027 (US10472367, Compound Formula I | US10919901, Compo...) Show SMILES C[C@@H](O)CNC(=O)c1ccc(cc1F)-c1cnc2ncc(Cc3ccc4ncccc4c3)n2n1 |r| Show InChI InChI=1S/C25H21FN6O2/c1-15(33)12-28-24(34)20-6-5-18(11-21(20)26)23-14-30-25-29-13-19(32(25)31-23)10-16-4-7-22-17(9-16)3-2-8-27-22/h2-9,11,13-15,33H,10,12H2,1H3,(H,28,34)/t15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Holdings Corporation; Incyte Corporation US Patent					Assay Description The compounds of the invention were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values for the inhibition of c-Met...				US Patent US10919901 (2021) BindingDB Entry DOI: 10.7270/Q2B85C72
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM98027 (US10472367, Compound Formula I | US10919901, Compo...) Show SMILES C[C@@H](O)CNC(=O)c1ccc(cc1F)-c1cnc2ncc(Cc3ccc4ncccc4c3)n2n1 |r| Show InChI InChI=1S/C25H21FN6O2/c1-15(33)12-28-24(34)20-6-5-18(11-21(20)26)23-14-30-25-29-13-19(32(25)31-23)10-16-4-7-22-17(9-16)3-2-8-27-22/h2-9,11,13-15,33H,10,12H2,1H3,(H,28,34)/t15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
INCYTE INCORPORATION; INCYTE HOLDINGS CORPORATION US Patent					Assay Description The compounds of the invention were screened in vitro for their ability to inhibit c-Met kinase activity. Briefly, histidine-tagged c-Met catalytic d...				US Patent US10472367 (2019) BindingDB Entry DOI: 10.7270/Q2639S3S
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM98027 (US10472367, Compound Formula I | US10919901, Compo...) Show SMILES C[C@@H](O)CNC(=O)c1ccc(cc1F)-c1cnc2ncc(Cc3ccc4ncccc4c3)n2n1 |r| Show InChI InChI=1S/C25H21FN6O2/c1-15(33)12-28-24(34)20-6-5-18(11-21(20)26)23-14-30-25-29-13-19(32(25)31-23)10-16-4-7-22-17(9-16)3-2-8-27-22/h2-9,11,13-15,33H,10,12H2,1H3,(H,28,34)/t15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.550	n/a	n/a	n/a	n/a	7.5	30
Incyte Holdings Corporation; Incyte Corporation US Patent					Assay Description The compounds of the invention were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values for the inhibition of c-M...				US Patent US9221824 (2015) BindingDB Entry DOI: 10.7270/Q2MP524M
					More data for this Ligand-Target Pair