Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor [T790M,L858R] (Homo sapiens (Human)) | BDBM149404 (AVL-301 | CHEMBL3545308 | CNX-419 | CO-1686 | Roci...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB US Patent | n/a | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a |
Jiangsu Medolution Ltd US Patent | Assay Description Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph... | US Patent US10167264 (2019) BindingDB Entry DOI: 10.7270/Q2CZ397P | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |