BindingDB PrimarySearch

Found 12 hits of kd for monomerid = 223311
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Ephrin type-A receptor 4 [29-209,M164A] (Homo sapiens (Human))	BDBM223311 (123C4) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	62	n/a	n/a	n/a	6.5	27
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
Sanford-Burnham-Prebys Medical Discovery Institute					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 [29-209,I159A] (Homo sapiens (Human))	BDBM223311 (123C4) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	290	n/a	n/a	n/a	6.5	27
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
Sanford-Burnham-Prebys Medical Discovery Institute					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 [29-209,D61G,E62G] (Homo sapiens (Human))	BDBM223311 (123C4) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	340	n/a	n/a	n/a	6.5	27
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
Sanford-Burnham-Prebys Medical Discovery Institute					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 [29-209,M60A] (Homo sapiens (Human))	BDBM223311 (123C4) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	350	n/a	n/a	n/a	6.5	27
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
Sanford-Burnham-Prebys Medical Discovery Institute					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 (Homo sapiens (Human))	BDBM223311 (123C4) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to N-terminal His tagged EphA4 LBD (unknown origin) (29 to 209 residues) expressed in Rosetta-Gami B(DE3) cells by isothermal titrat...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00608 BindingDB Entry DOI: 10.7270/Q2PK0KXT
TBA					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 [29-209] (Homo sapiens (Human))	BDBM223311 (123C4) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	420	n/a	n/a	n/a	6.5	27
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
Sanford-Burnham-Prebys Medical Discovery Institute					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 (Homo sapiens (Human))	BDBM223311 (123C4) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a
University of Parma Curated by ChEMBL					Assay Description Binding affinity to EphA4 ligand binding domain (unknown origin) by ITC				Eur J Med Chem 142: 152-162 (2017) Article DOI: 10.1016/j.ejmech.2017.07.029 BindingDB Entry DOI: 10.7270/Q29026GX
University of Parma Curated by ChEMBL					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 [29-209,I67A] (Homo sapiens (Human))	BDBM223311 (123C4) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	780	n/a	n/a	n/a	6.5	27
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
Sanford-Burnham-Prebys Medical Discovery Institute					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 [29-209,I59G] (Homo sapiens (Human))	BDBM223311 (123C4) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	3.66E+3	n/a	n/a	n/a	6.5	27
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
Sanford-Burnham-Prebys Medical Discovery Institute					More data for this Ligand-Target Pair
Ephrin type-A receptor 3 [29-207] (Homo sapiens (Human))	BDBM223311 (123C4) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	4.55E+3	n/a	n/a	n/a	6.5	27
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
Sanford-Burnham-Prebys Medical Discovery Institute					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 [29-209,I59A] (Homo sapiens (Human))	BDBM223311 (123C4) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	9.09E+3	n/a	n/a	n/a	6.5	27
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
Sanford-Burnham-Prebys Medical Discovery Institute					More data for this Ligand-Target Pair
Ephrin type-A receptor 3 (Homo sapiens (Human))	BDBM223311 (123C4) Show SMILES Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to N-terminal His tagged EphA3 LBD (unknown origin) expressed in Rosetta-Gami B(DE3) cells by isothermal titration calorimetry				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00608 BindingDB Entry DOI: 10.7270/Q2PK0KXT
TBA					More data for this Ligand-Target Pair