Found 3 hits of kd for monomerid = 286614 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Peptidyl-prolyl cis-trans isomerase F, mitochondrial
(Homo sapiens (Human)) | BDBM286614
(US9566312, Compound 2.20.1)Show SMILES CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H]([C@H](C)COC[C@@H]2CN(CC)CCO2)N(C)C(=O)[C@@H](C)N(C)C1=O)C(C)C |r| Show InChI InChI=1S/C69H124N12O14/c1-26-29-30-44(14)58(82)57-62(86)72-50(27-2)65(89)74(19)48(18)64(88)79(24)56(45(15)37-94-38-49-36-81(28-3)31-32-95-49)61(85)73-54(42(10)11)68(92)75(20)51(33-39(4)5)60(84)70-46(16)59(83)71-47(17)63(87)76(21)52(34-40(6)7)66(90)77(22)53(35-41(8)9)67(91)78(23)55(43(12)13)69(93)80(57)25/h26,29,39-58,82H,27-28,30-38H2,1-25H3,(H,70,84)(H,71,83)(H,72,86)(H,73,85)/b29-26+/t44-,45-,46+,47-,48-,49+,50+,51+,52+,53+,54+,55+,56+,57+,58-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | 7.4 | n/a |
Novartis AG
US Patent
| Assay Description
Binding of inhibitors to expressed cyclophilins was determined using surface plasmon resonance (SPR) experiments. Briefly, avi-tagged cyclophilin pro... |
US Patent US9566312 (2017)
BindingDB Entry DOI: 10.7270/Q2K939J1 |
More data for this
Ligand-Target Pair | |
Peptidyl-prolyl cis-trans isomerase A
(Homo sapiens (Human)) | BDBM286614
(US9566312, Compound 2.20.1)Show SMILES CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H]([C@H](C)COC[C@@H]2CN(CC)CCO2)N(C)C(=O)[C@@H](C)N(C)C1=O)C(C)C |r| Show InChI InChI=1S/C69H124N12O14/c1-26-29-30-44(14)58(82)57-62(86)72-50(27-2)65(89)74(19)48(18)64(88)79(24)56(45(15)37-94-38-49-36-81(28-3)31-32-95-49)61(85)73-54(42(10)11)68(92)75(20)51(33-39(4)5)60(84)70-46(16)59(83)71-47(17)63(87)76(21)52(34-40(6)7)66(90)77(22)53(35-41(8)9)67(91)78(23)55(43(12)13)69(93)80(57)25/h26,29,39-58,82H,27-28,30-38H2,1-25H3,(H,70,84)(H,71,83)(H,72,86)(H,73,85)/b29-26+/t44-,45-,46+,47-,48-,49+,50+,51+,52+,53+,54+,55+,56+,57+,58-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | 0.700 | n/a | n/a | n/a | 7.4 | n/a |
Novartis AG
US Patent
| Assay Description
Binding of inhibitors to expressed cyclophilins was determined using surface plasmon resonance (SPR) experiments. Briefly, avi-tagged cyclophilin pro... |
US Patent US9566312 (2017)
BindingDB Entry DOI: 10.7270/Q2K939J1 |
More data for this
Ligand-Target Pair | |
Peptidyl-prolyl cis-trans isomerase B
(Homo sapiens (Human)) | BDBM286614
(US9566312, Compound 2.20.1)Show SMILES CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H]([C@H](C)COC[C@@H]2CN(CC)CCO2)N(C)C(=O)[C@@H](C)N(C)C1=O)C(C)C |r| Show InChI InChI=1S/C69H124N12O14/c1-26-29-30-44(14)58(82)57-62(86)72-50(27-2)65(89)74(19)48(18)64(88)79(24)56(45(15)37-94-38-49-36-81(28-3)31-32-95-49)61(85)73-54(42(10)11)68(92)75(20)51(33-39(4)5)60(84)70-46(16)59(83)71-47(17)63(87)76(21)52(34-40(6)7)66(90)77(22)53(35-41(8)9)67(91)78(23)55(43(12)13)69(93)80(57)25/h26,29,39-58,82H,27-28,30-38H2,1-25H3,(H,70,84)(H,71,83)(H,72,86)(H,73,85)/b29-26+/t44-,45-,46+,47-,48-,49+,50+,51+,52+,53+,54+,55+,56+,57+,58-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | 0.700 | n/a | n/a | n/a | 7.4 | n/a |
Novartis AG
US Patent
| Assay Description
Binding of inhibitors to expressed cyclophilins was determined using surface plasmon resonance (SPR) experiments. Briefly, avi-tagged cyclophilin pro... |
US Patent US9566312 (2017)
BindingDB Entry DOI: 10.7270/Q2K939J1 |
More data for this
Ligand-Target Pair | |
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