Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2B (RAT) | BDBM29135 (CHEMBL11608 | cid_5610 | p-Tyramine | tyramine) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | 7.94E+3 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonistic activity of corresponding methoxy compound against serotonin 5-HT receptor | J Med Chem 23: 990-4 (1980) BindingDB Entry DOI: 10.7270/Q2668FCW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM29135 (CHEMBL11608 | cid_5610 | p-Tyramine | tyramine) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | n/a | 2.00E+6 | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Curated by ChEMBL | Assay Description Binding affinity to BACE1 by surface plasmon resonance method | Bioorg Med Chem Lett 18: 1304-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.032 BindingDB Entry DOI: 10.7270/Q2Z60PW9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |