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Compile Data Set for Download or QSAR

Found 2 hits of kd for monomerid = 50074243   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50074243
PNG
((S)-4-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)...)
Show SMILES CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CCC(O)=O)C(=O)NCc1ccccc1
Show InChI InChI=1S/C23H28N3O9P/c1-15(27)25-20(13-16-7-9-18(10-8-16)35-36(32,33)34)23(31)26-19(11-12-21(28)29)22(30)24-14-17-5-3-2-4-6-17/h2-10,19-20H,11-14H2,1H3,(H,24,30)(H,25,27)(H,26,31)(H,28,29)(H2,32,33,34)/t19-,20-/m0/s1
PDB

UniProtKB/SwissProt

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AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/a 1.50E+3n/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Dissociation constant for p56 Lck tyrosine kinase SH2 domain binding to C-terminal ITAM2 phosphopeptide

J Med Chem 47: 3502-11 (2004)


Article DOI: 10.1021/jm030470e
BindingDB Entry DOI: 10.7270/Q28915B4
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50074243
PNG
((S)-4-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)...)
Show SMILES CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CCC(O)=O)C(=O)NCc1ccccc1
Show InChI InChI=1S/C23H28N3O9P/c1-15(27)25-20(13-16-7-9-18(10-8-16)35-36(32,33)34)23(31)26-19(11-12-21(28)29)22(30)24-14-17-5-3-2-4-6-17/h2-10,19-20H,11-14H2,1H3,(H,24,30)(H,25,27)(H,26,31)(H,28,29)(H2,32,33,34)/t19-,20-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/a 1.50E+3n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity of the compound against p56 Lck tyrosine kinase SH2 domain was measured using glutathione S-transferase (GST) fusion protein

J Med Chem 42: 722-9 (1999)


Article DOI: 10.1021/jm980612i
BindingDB Entry DOI: 10.7270/Q2Q23ZDX
More data for this
Ligand-Target Pair