Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prothrombin (Homo sapiens (Human)) | BDBM50442881 (SILYBIN A) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a |
University of Lodz Curated by ChEMBL | Assay Description Inhibition of human thrombin assessed as equilibrium dissociation constant at 50 to 1000 uM by BIAcore analysis | Med Chem Res 23: 2324-2337 (2014) Article DOI: 10.1007/s00044-013-0829-4 BindingDB Entry DOI: 10.7270/Q2377B7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heat shock protein HSP 90-alpha/90-beta (Homo sapiens (Human)) | BDBM50442881 (SILYBIN A) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 5.00E+5 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to HSP90 C-terminal domain (unknown origin) by biochemical assay | Citation and Details Article DOI: 10.1039/d0md00387e BindingDB Entry DOI: 10.7270/Q29K4FZQ | |||||||||||
More data for this Ligand-Target Pair |