Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thiamine-binding periplasmic protein (Escherichia coli (strain K12)) | BDBM92962 (ThDP) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 7.40 | n/a | n/a | n/a | n/a | n/a |
Cornell University | Assay Description the kd for ThOH, ThMP and ThDP were determined using titration experiments in which the change in the intrinsic protein fluorescence was monitored as... | Biochemistry 47: 1346-57 (2008) Article DOI: 10.1021/bi7018282 BindingDB Entry DOI: 10.7270/Q28C9TVF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Deinococcus radiodurans (strain ATCC 13939 / DSM 2...) | BDBM92962 (ThDP) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 114 | n/a | n/a | n/a | n/a | n/a |
University of Groningen Curated by ChEMBL | Assay Description Binding affinity to Deinococcus radiodurans DXS | J Med Chem 57: 9740-63 (2014) Article DOI: 10.1021/jm5010978 BindingDB Entry DOI: 10.7270/Q29K4CVJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM92962 (ThDP) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a |
University of Groningen Curated by ChEMBL | Assay Description Binding affinity to Mycobacterium tuberculosis DXS | J Med Chem 57: 9740-63 (2014) Article DOI: 10.1021/jm5010978 BindingDB Entry DOI: 10.7270/Q29K4CVJ | |||||||||||
More data for this Ligand-Target Pair |