Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tubulin--tyrosine ligase (Homo sapiens (Human)) | BDBM18129 ((2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid | L...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 2.50E+4 | -27.3 | n/a | n/a | n/a | n/a | n/a | 6.8 | 37 |
Binghamton University | Assay Description Inhibition of [3H]-L-tyrosine incorporation into tubulin by enzyme tubulin tyrosine ligase (TTL). | ACS Chem Biol 5: 777-85 (2010) Article DOI: 10.1021/cb100060v BindingDB Entry DOI: 10.7270/Q25H7DM1 | |||||||||||
More data for this Ligand-Target Pair |