Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thymidine phosphorylase (Homo sapiens (Human)) | BDBM20073 (5-Substituted-6-chlorouracil, 13c | 6-chloro-5-[(1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 410 | -37.9 | n/a | n/a | n/a | n/a | n/a | 6.4 | 37 |
Gilead Sciences Inc. | Assay Description The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b... | J Med Chem 50: 6016-23 (2007) Article DOI: 10.1021/jm070644i BindingDB Entry DOI: 10.7270/Q2M043PX | |||||||||||
More data for this Ligand-Target Pair |