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Compile Data Set for Download or QSAR

Found 3 hits of ki for monomerid = 286346   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein-tyrosine kinase 2-beta


(Homo sapiens (Human))
BDBM286346
PNG
(US11220518, Ex. No. K4 | US11780853, Example K4 | ...)
Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CCOC)C[C@@H]2C)C3(C)C)n1 |r|
Show InChI InChI=1S/C23H35FN8O3/c1-7-35-21-25-10-17(24)20(27-21)26-19-16-13-32(23(4,5)18(16)28-29-19)22(33)31-12-14(2)30(8-9-34-6)11-15(31)3/h10,14-15H,7-9,11-13H2,1-6H3,(H2,25,26,27,28,29)/t14-,15+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
3.33n/an/an/an/an/an/a7.4n/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)


BindingDB Entry DOI: 10.7270/Q2ZK5JPN
More data for this
Ligand-Target Pair
Protein kinase C beta type Isoform 2


(Homo sapiens (Human))
BDBM286346
PNG
(US11220518, Ex. No. K4 | US11780853, Example K4 | ...)
Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CCOC)C[C@@H]2C)C3(C)C)n1 |r|
Show InChI InChI=1S/C23H35FN8O3/c1-7-35-21-25-10-17(24)20(27-21)26-19-16-13-32(23(4,5)18(16)28-29-19)22(33)31-12-14(2)30(8-9-34-6)11-15(31)3/h10,14-15H,7-9,11-13H2,1-6H3,(H2,25,26,27,28,29)/t14-,15+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
3.33n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Protein kinase C beta type


(Homo sapiens (Human))
BDBM286346
PNG
(US11220518, Ex. No. K4 | US11780853, Example K4 | ...)
Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CCOC)C[C@@H]2C)C3(C)C)n1 |r|
Show InChI InChI=1S/C23H35FN8O3/c1-7-35-21-25-10-17(24)20(27-21)26-19-16-13-32(23(4,5)18(16)28-29-19)22(33)31-12-14(2)30(8-9-34-6)11-15(31)3/h10,14-15H,7-9,11-13H2,1-6H3,(H2,25,26,27,28,29)/t14-,15+/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
3.33n/an/an/an/an/an/an/an/a


TBA

Assay Description
A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a...


Citation and Details

BindingDB Entry DOI: 10.7270/Q28S4T3T
More data for this
Ligand-Target Pair