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Compile Data Set for Download or QSAR

Found 1 hit of ki for monomerid = 323369   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase ATR


(Homo sapiens (Human))		BDBM323369
PNG
(US9630956, Compound I-106)
Show SMILES CC(N)c1cccc(c1)-c1cc(on1)-c1nc(cnc1N)-c1ccc(=O)n(CC2CC2C)c1
Show InChI InChI=1S/C25H26N6O2/c1-14-8-19(14)13-31-12-18(6-7-23(31)32)21-11-28-25(27)24(29-21)22-10-20(30-33-22)17-5-3-4-16(9-17)15(2)26/h3-7,9-12,14-15,19H,8,13,26H2,1-2H3,(H2,27,28)
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US Patent
<5n/an/an/an/an/an/an/an/a



Vertex Pharmaceuticals Incorporated

US Patent


Assay Description
Compounds were screened for their ability to inhibit ATR kinase using a radioactive-phosphate incorporation assay. Assays were carried out in a mixtu...

US Patent US9630956 (2017)


BindingDB Entry DOI: 10.7270/Q2X63Q2S
More data for this
Ligand-Target Pair