Compile Data Set for Download or QSAR

Found 2 hits of ki for monomerid = 324577   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM324577 (2-[3-[2-[[1-[2-(4- methylpiperazin-1-yl)-2- oxo-et...) Show SMILES CN1CCN(CC1)C(=O)Cn1cc(Nc2nc3c(cccn3n2)N2CC3CCC(C2)N3C(=O)c2ccccc2C#N)cn1 Show InChI InChI=1S/C30H33N11O2/c1-36-11-13-37(14-12-36)27(42)20-39-17-22(16-32-39)33-30-34-28-26(7-4-10-40(28)35-30)38-18-23-8-9-24(19-38)41(23)29(43)25-6-3-2-5-21(25)15-31/h2-7,10,16-17,23-24H,8-9,11-14,18-20H2,1H3,(H,33,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...				US Patent US10189836 (2019) BindingDB Entry DOI: 10.7270/Q2G162XH
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM324577 (2-[3-[2-[[1-[2-(4- methylpiperazin-1-yl)-2- oxo-et...) Show SMILES CN1CCN(CC1)C(=O)Cn1cc(Nc2nc3c(cccn3n2)N2CC3CCC(C2)N3C(=O)c2ccccc2C#N)cn1 Show InChI InChI=1S/C30H33N11O2/c1-36-11-13-37(14-12-36)27(42)20-39-17-22(16-32-39)33-30-34-28-26(7-4-10-40(28)35-30)38-18-23-8-9-24(19-38)41(23)29(43)25-6-3-2-5-21(25)15-31/h2-7,10,16-17,23-24H,8-9,11-14,18-20H2,1H3,(H,33,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...				US Patent US10189836 (2019) BindingDB Entry DOI: 10.7270/Q2G162XH
					More data for this Ligand-Target Pair