BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits of ki for monomerid = 355373   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase


(Macaca mulatta (Rhesus macaque))
BDBM355373
PNG
(N-{(1R)-1-[3-fluoro-4- (trifluoromethoxy)phenyl]-2...)
Show SMILES COc1ccc(Cc2nc(cc(=O)[nH]2)C(=O)N[C@@H](c2ccc(OC(F)(F)F)c(F)c2)C(C)(C)C)cc1 |r|
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.600n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Corp.; MSD R & D (China) Co. LTD.

US Patent


Assay Description
In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...


US Patent US9815796 (2017)


BindingDB Entry DOI: 10.7270/Q2V69MQQ
More data for this
Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM355373
PNG
(N-{(1R)-1-[3-fluoro-4- (trifluoromethoxy)phenyl]-2...)
Show SMILES COc1ccc(Cc2nc(cc(=O)[nH]2)C(=O)N[C@@H](c2ccc(OC(F)(F)F)c(F)c2)C(C)(C)C)cc1 |r|
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.690n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Corp.; MSD R & D (China) Co. LTD.

US Patent


Assay Description
In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...


US Patent US9815796 (2017)


BindingDB Entry DOI: 10.7270/Q2V69MQQ
More data for this
Ligand-Target Pair