BindingDB PrimarySearch

Found 13 hits of ki for monomerid = 50014260
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Adenosine receptor A1 (BOVINE)	BDBM50014260 (3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione \| 3,7...) Show SMILES Cn1cnc2n(C)c(=O)[nH]c(=O)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 330: 212-21 (1985) Article DOI: 10.1007/bf00572436 BindingDB Entry DOI: 10.7270/Q2RB7334
TBA Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50014260 (3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione \| 3,7...) Show SMILES Cn1cnc2n(C)c(=O)[nH]c(=O)c12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 330: 212-21 (1985) Article DOI: 10.1007/bf00572436 BindingDB Entry DOI: 10.7270/Q2RB7334
TBA Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50014260 (3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione \| 3,7...) Show SMILES Cn1cnc2n(C)c(=O)[nH]c(=O)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert/Parke-Davis Pharmaceutical Research Curated by PDSP K_i Database									Mol Pharmacol 29: 331-46 (1986) BindingDB Entry DOI: 10.7270/Q2MK6BDV
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50014260 (3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione \| 3,7...) Show SMILES Cn1cnc2n(C)c(=O)[nH]c(=O)c12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert/Parke-Davis Pharmaceutical Research Curated by PDSP K_i Database									Mol Pharmacol 29: 331-46 (1986) BindingDB Entry DOI: 10.7270/Q2MK6BDV
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50014260 (3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione \| 3,7...) Show SMILES Cn1cnc2n(C)c(=O)[nH]c(=O)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 330: 212-21 (1985) Article DOI: 10.1007/bf00572436 BindingDB Entry DOI: 10.7270/Q2RB7334
TBA Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mus musculus (mouse))	BDBM50014260 (3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione \| 3,7...) Show SMILES Cn1cnc2n(C)c(=O)[nH]c(=O)c12 Show InChI	MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
J. Uriach & Cía, S.A. Curated by ChEMBL					Assay Description Inhibitory activity against dihydrofolate reductase (DHFR) enzyme from chicken liver				J Med Chem 40: 547-58 (1997) Article DOI: 10.1021/jm9604383
J. Uriach & Cía, S.A. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50014260 (3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione \| 3,7...) Show SMILES Cn1cnc2n(C)c(=O)[nH]c(=O)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.03E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
J. Uriach & Cía, S.A. Curated by ChEMBL					Assay Description Inhibitory activity against dihydrofolate reductase (DHFR) enzyme from chicken liver				J Med Chem 40: 547-58 (1997) Article DOI: 10.1021/jm9604383
J. Uriach & Cía, S.A. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50014260 (3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione \| 3,7...) Show SMILES Cn1cnc2n(C)c(=O)[nH]c(=O)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	1.05E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Binding affinity for Adenosine A1 receptor from rat brain using [3H]-PIA as radioligand				J Med Chem 33: 2818-21 (1990) BindingDB Entry DOI: 10.7270/Q2C53JVQ
National Institute of Diabetes Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50014260 (3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione \| 3,7...) Show SMILES Cn1cnc2n(C)c(=O)[nH]c(=O)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	1.05E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmazeutische Chemie Curated by ChEMBL					Assay Description Binding affinity at Adenosine A1 receptor in rat brain cortical membrane using [3H]-N6-R-phenylisopropyladenosine (R-PIA) as radioligand				J Med Chem 36: 3341-9 (1993) BindingDB Entry DOI: 10.7270/Q26Q1W9W
Pharmazeutische Chemie Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50014260 (3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione \| 3,7...) Show SMILES Cn1cnc2n(C)c(=O)[nH]c(=O)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	1.05E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
J. Uriach & Cía, S.A. Curated by ChEMBL					Assay Description Ability to inhibit U-46,619-induced contraction of isolated strips of rabbit thoracic aorta, which is the measure of thromboxane receptor antagonism				J Med Chem 40: 547-58 (1997) Article DOI: 10.1021/jm9604383
J. Uriach & Cía, S.A. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50014260 (3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione \| 3,7...) Show SMILES Cn1cnc2n(C)c(=O)[nH]c(=O)c12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
J. Uriach & Cía, S.A. Curated by ChEMBL					Assay Description Ability to inhibit U-46,619-induced contraction of isolated strips of guinea pig tracheal chain, which is the measure of thromboxane receptor antagon...				J Med Chem 40: 547-58 (1997) Article DOI: 10.1021/jm9604383
J. Uriach & Cía, S.A. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2a/A2b (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50014260 (3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione \| 3,7...) Show SMILES Cn1cnc2n(C)c(=O)[nH]c(=O)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Binding affinity for Adenosine A2 receptor from rat striatum using [3H]NECA as radioligand				J Med Chem 33: 2818-21 (1990) BindingDB Entry DOI: 10.7270/Q2C53JVQ
National Institute of Diabetes Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2a/A2b (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50014260 (3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione \| 3,7...) Show SMILES Cn1cnc2n(C)c(=O)[nH]c(=O)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Antagonism of N-ethylcarboxamido adenosine-stimulated adenylate cyclase associated with stimulation of Adenosine A2 receptor of rat PC12 membranes				J Med Chem 33: 2818-21 (1990) BindingDB Entry DOI: 10.7270/Q2C53JVQ
National Institute of Diabetes Curated by ChEMBL					More data for this Ligand-Target Pair