Found 10 hits of ki for monomerid = 50030630 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Metabotropic glutamate receptor 1
(RAT) | BDBM50030630
((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16) | PDB
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| Article
PubMed
| 98.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
| |
Mol Pharmacol 63: 1082-93 (2003)
Article DOI: 10.1124/mol.63.5.1082
BindingDB Entry DOI: 10.7270/Q2BV7F62 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50030630
((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16) | PDB
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| Article
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| 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by PDSP Ki Database
| |
Life Sci 73: 371-9 (2003)
Article DOI: 10.1016/s0024-3205(03)00272-8
BindingDB Entry DOI: 10.7270/Q2KD1WHW |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50030630
((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16) | PDB
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| Article
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| 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University
Curated by PDSP Ki Database
| |
Annu Rev Pharmacol Toxicol 37: 205-37 (1997)
Article DOI: 10.1146/annurev.pharmtox.37.1.205
BindingDB Entry DOI: 10.7270/Q2M043ZH |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50030630
((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16) | PDB
MMDB
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| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche
Curated by PDSP Ki Database
| |
J Neurochem 75: 2590-601 (2000)
Article DOI: 10.1046/j.1471-4159.2000.0752590.x
BindingDB Entry DOI: 10.7270/Q2J67FGZ |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50030630
((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16) | PDB
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| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche
Curated by PDSP Ki Database
| |
J Neurochem 75: 2590-601 (2000)
Article DOI: 10.1046/j.1471-4159.2000.0752590.x
BindingDB Entry DOI: 10.7270/Q2J67FGZ |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(RAT) | BDBM50030630
((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16) | PDB
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| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
| |
Mol Pharmacol 63: 1082-93 (2003)
Article DOI: 10.1124/mol.63.5.1082
BindingDB Entry DOI: 10.7270/Q2BV7F62 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50030630
((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16) | PDB
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| 2.14E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human metabotropic glutamate receptor 1 |
J Med Chem 43: 2609-45 (2000)
BindingDB Entry DOI: 10.7270/Q2DZ090Q |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50030630
((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16) | PDB
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| >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4) |
J Med Chem 43: 2609-45 (2000)
BindingDB Entry DOI: 10.7270/Q2DZ090Q |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50030630
((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16) | PDB
MMDB
KEGG
UniProtKB/SwissProt
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DrugBank
antibodypedia
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| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
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| PubMed
| >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy
Curated by ChEMBL
| Assay Description
Agonist potency against cloned metabotropic glutamate receptor 5 |
J Med Chem 43: 2609-45 (2000)
BindingDB Entry DOI: 10.7270/Q2DZ090Q |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50030630
((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16) | PDB
UniProtKB/SwissProt
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CHEMBL
MCE
PC cid
PC sid
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| >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy
Curated by ChEMBL
| Assay Description
Antagonist potency against cloned Metabotropic glutamate receptor 2 |
J Med Chem 43: 2609-45 (2000)
BindingDB Entry DOI: 10.7270/Q2DZ090Q |
More data for this
Ligand-Target Pair | |
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