BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit of ki for monomerid = 50037338   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neutrophil elastase


(Homo sapiens (Human))		BDBM50037338
PNG
(CHEMBL325234 | {6-(3-Chloro-phenyl)-2-oxo-1-[(3,3,...)
Show SMILES CC(C)C(NC(=O)Cn1c(ccc(NC(=O)OCc2ccccc2)c1=O)-c1cccc(Cl)c1)C(=O)C(F)(F)F
Show InChI InChI=1S/C27H25ClF3N3O5/c1-16(2)23(24(36)27(29,30)31)33-22(35)14-34-21(18-9-6-10-19(28)13-18)12-11-20(25(34)37)32-26(38)39-15-17-7-4-3-5-8-17/h3-13,16,23H,14-15H2,1-2H3,(H,32,38)(H,33,35)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 3.5n/an/an/an/an/an/an/an/a



ZENECA Pharmaceuticals Group

Curated by ChEMBL


Assay Description
Tested for inhibitory activity against human leukocyte elastase(HLE) enzyme

J Med Chem 37: 3303-12 (1994)


BindingDB Entry DOI: 10.7270/Q2SB44SP
More data for this
Ligand-Target Pair