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Compile Data Set for Download or QSAR

Found 2 hits of ki for monomerid = 50054239   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))
BDBM50054239
PNG
(CHEMBL78035 | [4-(3,6-Dihydro-2H-pyridin-1-yl)-6-m...)
Show SMILES Cc1cc(C)c(Nc2nc(C)nc(n2)N2CCC=CC2)c(C)c1 |c:18|
Show InChI InChI=1S/C18H23N5/c1-12-10-13(2)16(14(3)11-12)21-17-19-15(4)20-18(22-17)23-8-6-5-7-9-23/h5-6,10-11H,7-9H2,1-4H3,(H,19,20,21,22)
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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.05E+3n/an/an/an/an/an/an/an/a



The University of Wollongong

Curated by ChEMBL


Assay Description
Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.


J Med Chem 42: 2351-7 (1999)


Article DOI: 10.1021/jm9900117
BindingDB Entry DOI: 10.7270/Q2WS8SF0
More data for this
Ligand-Target Pair
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))
BDBM50054239
PNG
(CHEMBL78035 | [4-(3,6-Dihydro-2H-pyridin-1-yl)-6-m...)
Show SMILES Cc1cc(C)c(Nc2nc(C)nc(n2)N2CCC=CC2)c(C)c1 |c:18|
Show InChI InChI=1S/C18H23N5/c1-12-10-13(2)16(14(3)11-12)21-17-19-15(4)20-18(22-17)23-8-6-5-7-9-23/h5-6,10-11H,7-9H2,1-4H3,(H,19,20,21,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.05E+3n/an/an/an/an/an/an/an/a



Neurocrine Biosciences

Curated by ChEMBL


Assay Description
Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1


J Med Chem 39: 4354-7 (1996)


Article DOI: 10.1021/jm960148m
BindingDB Entry DOI: 10.7270/Q2DR2TK7
More data for this
Ligand-Target Pair