BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits of ki for monomerid = 50057084   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Stromelysin-1


(Homo sapiens (Human))
BDBM50057084
PNG
(4'-[(3R,5S)-5-Carboxy-3-((S)-2,2-dimethyl-1-methyl...)
Show SMILES CCCC[C@@H](C[C@@H](CCc1ccc(cc1)-c1ccc(cc1)C(=O)OC)C(=O)N[C@H](C(=O)NC)C(C)(C)C)C(O)=O
Show InChI InChI=1S/C32H44N2O6/c1-7-8-9-26(30(37)38)20-25(28(35)34-27(29(36)33-5)32(2,3)4)15-12-21-10-13-22(14-11-21)23-16-18-24(19-17-23)31(39)40-6/h10-11,13-14,16-19,25-27H,7-9,12,15,20H2,1-6H3,(H,33,36)(H,34,35)(H,37,38)/t25-,26+,27-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
31n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human stromelysin-1 (Matrix metalloproteinase-3)


J Med Chem 40: 1026-40 (1997)


Article DOI: 10.1021/jm960465t
BindingDB Entry DOI: 10.7270/Q2H70DXR
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM50057084
PNG
(4'-[(3R,5S)-5-Carboxy-3-((S)-2,2-dimethyl-1-methyl...)
Show SMILES CCCC[C@@H](C[C@@H](CCc1ccc(cc1)-c1ccc(cc1)C(=O)OC)C(=O)N[C@H](C(=O)NC)C(C)(C)C)C(O)=O
Show InChI InChI=1S/C32H44N2O6/c1-7-8-9-26(30(37)38)20-25(28(35)34-27(29(36)33-5)32(2,3)4)15-12-21-10-13-22(14-11-21)23-16-18-24(19-17-23)31(39)40-6/h10-11,13-14,16-19,25-27H,7-9,12,15,20H2,1-6H3,(H,33,36)(H,34,35)(H,37,38)/t25-,26+,27-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
32n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of gelatinase A (Matrix metalloproteinase-2)


J Med Chem 40: 1026-40 (1997)


Article DOI: 10.1021/jm960465t
BindingDB Entry DOI: 10.7270/Q2H70DXR
More data for this
Ligand-Target Pair