BindingDB PrimarySearch

Found 13 hits of ki for monomerid = 50057762
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50057762 (CHEMBL3323011 \| US9598387, Compound 113 \| US996974...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description Stably transfected HEK cells expressing the human D2-long and the D3 dopamine receptor were developed using the pIRESneo2 bicistronic expression vect...				J Med Chem 52: 1935-42 (2009) BindingDB Entry DOI: 10.7270/Q2HD7Z0N
Universita degli Studi di Roma La Sapienza					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50057762 (CHEMBL3323011 \| US9598387, Compound 113 \| US996974...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]IABN from human D3R expressed in HEK293 cell membranes by gamma counting method				J Med Chem 57: 7042-60 (2014) Article DOI: 10.1021/jm500801r BindingDB Entry DOI: 10.7270/Q27D2WSR
Southern Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50057762 (CHEMBL3323011 \| US9598387, Compound 113 \| US996974...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute US Patent					Assay Description The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...				US Patent US9598387 (2017) BindingDB Entry DOI: 10.7270/Q2QZ2D1Z
Southern Research Institute US Patent					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50057762 (CHEMBL3323011 \| US9598387, Compound 113 \| US996974...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]IABN from wild type human D3R expressed in HEK293 cell membranes by gamma counting method				J Med Chem 57: 7042-60 (2014) Article DOI: 10.1021/jm500801r BindingDB Entry DOI: 10.7270/Q27D2WSR
Southern Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50057762 (CHEMBL3323011 \| US9598387, Compound 113 \| US996974...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]IABN from human D3R S182I mutant expressed in HEK293 cell membranes by gamma counting method				J Med Chem 57: 7042-60 (2014) Article DOI: 10.1021/jm500801r BindingDB Entry DOI: 10.7270/Q27D2WSR
Southern Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50057762 (CHEMBL3323011 \| US9598387, Compound 113 \| US996974...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]IABN from human D3R E90A mutant expressed in HEK293 cell membranes by gamma counting method				J Med Chem 57: 7042-60 (2014) Article DOI: 10.1021/jm500801r BindingDB Entry DOI: 10.7270/Q27D2WSR
Southern Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50057762 (CHEMBL3323011 \| US9598387, Compound 113 \| US996974...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]IABN from human D3R E90Q mutant expressed in HEK293 cell membranes by gamma counting method				J Med Chem 57: 7042-60 (2014) Article DOI: 10.1021/jm500801r BindingDB Entry DOI: 10.7270/Q27D2WSR
Southern Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50057762 (CHEMBL3323011 \| US9598387, Compound 113 \| US996974...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]IABN from chimeric human D3 receptor possessing extracellular loop II of D2 receptor expressed in HEK293 cell membranes by gamm...				J Med Chem 57: 7042-60 (2014) Article DOI: 10.1021/jm500801r BindingDB Entry DOI: 10.7270/Q27D2WSR
Southern Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50057762 (CHEMBL3323011 \| US9598387, Compound 113 \| US996974...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	148	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]IABN from chimeric human D2 receptor possessing extracellular loop II of D3 receptor expressed in HEK293 cell membranes by gamm...				J Med Chem 57: 7042-60 (2014) Article DOI: 10.1021/jm500801r BindingDB Entry DOI: 10.7270/Q27D2WSR
Southern Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50057762 (CHEMBL3323011 \| US9598387, Compound 113 \| US996974...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	511	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description Stably transfected HEK cells expressing the human D2-long and the D3 dopamine receptor were developed using the pIRESneo2 bicistronic expression vect...				J Med Chem 52: 1935-42 (2009) BindingDB Entry DOI: 10.7270/Q2HD7Z0N
Universita degli Studi di Roma La Sapienza					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50057762 (CHEMBL3323011 \| US9598387, Compound 113 \| US996974...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	511	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute US Patent					Assay Description The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...				US Patent US9598387 (2017) BindingDB Entry DOI: 10.7270/Q2QZ2D1Z
Southern Research Institute US Patent					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50057762 (CHEMBL3323011 \| US9598387, Compound 113 \| US996974...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	511	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]IABN from human D2LR expressed in HEK293 cell membranes by gamma counting method				J Med Chem 57: 7042-60 (2014) Article DOI: 10.1021/jm500801r BindingDB Entry DOI: 10.7270/Q27D2WSR
Southern Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50057762 (CHEMBL3323011 \| US9598387, Compound 113 \| US996974...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	702	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]IABN from wild type human D2R expressed in HEK293 cell membranes by gamma counting method				J Med Chem 57: 7042-60 (2014) Article DOI: 10.1021/jm500801r BindingDB Entry DOI: 10.7270/Q27D2WSR
Southern Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair