Found 2 hits of ki for monomerid = 50096629 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prothrombin
(Homo sapiens (Human)) | BDBM50096629
(3-(4-Amino-cyclohexyl)-2-oxo-3-[((6S,8aS)-4-oxo-2-...)Show SMILES [H][C@@]12CC[C@H](N1C(=O)CN(C2)S(=O)(=O)Cc1ccccc1)C(=O)NC([C@H]1CC[C@H](N)CC1)C(=O)C(O)=O |wU:4.23,28.31,1.0,wD:25.27,(5.13,2.97,;5.13,1.42,;6.6,1.89,;7.51,.65,;6.6,-.59,;5.13,-.12,;3.8,-.9,;3.8,-2.44,;2.46,-.12,;2.46,1.42,;3.8,2.19,;1.11,2.19,;.34,.84,;1.88,3.55,;-.23,2.96,;-.25,4.5,;-1.58,5.28,;-1.58,6.83,;-.25,7.6,;1.08,6.83,;1.08,5.28,;7.07,-2.07,;6.04,-3.21,;8.57,-2.39,;9.05,-3.87,;8,-5.01,;6.51,-4.68,;5.47,-5.81,;5.95,-7.27,;4.92,-8.43,;7.44,-7.61,;8.47,-6.48,;10.55,-4.19,;11.58,-3.06,;11.02,-5.67,;12.42,-6.3,;9.87,-6.69,)| Show InChI InChI=1S/C24H32N4O7S/c25-17-8-6-16(7-9-17)21(22(30)24(32)33)26-23(31)19-11-10-18-12-27(13-20(29)28(18)19)36(34,35)14-15-4-2-1-3-5-15/h1-5,16-19,21H,6-14,25H2,(H,26,31)(H,32,33)/t16-,17-,18-,19-,21?/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.0900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
BioChem Pharma Inc.
Curated by ChEMBL
| Assay Description
In vitro activity of the compound against human alpha thrombin was determined |
Bioorg Med Chem Lett 11: 287-90 (2001)
BindingDB Entry DOI: 10.7270/Q2P55MS6 |
More data for this
Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50096629
(3-(4-Amino-cyclohexyl)-2-oxo-3-[((6S,8aS)-4-oxo-2-...)Show SMILES [H][C@@]12CC[C@H](N1C(=O)CN(C2)S(=O)(=O)Cc1ccccc1)C(=O)NC([C@H]1CC[C@H](N)CC1)C(=O)C(O)=O |wU:4.23,28.31,1.0,wD:25.27,(5.13,2.97,;5.13,1.42,;6.6,1.89,;7.51,.65,;6.6,-.59,;5.13,-.12,;3.8,-.9,;3.8,-2.44,;2.46,-.12,;2.46,1.42,;3.8,2.19,;1.11,2.19,;.34,.84,;1.88,3.55,;-.23,2.96,;-.25,4.5,;-1.58,5.28,;-1.58,6.83,;-.25,7.6,;1.08,6.83,;1.08,5.28,;7.07,-2.07,;6.04,-3.21,;8.57,-2.39,;9.05,-3.87,;8,-5.01,;6.51,-4.68,;5.47,-5.81,;5.95,-7.27,;4.92,-8.43,;7.44,-7.61,;8.47,-6.48,;10.55,-4.19,;11.58,-3.06,;11.02,-5.67,;12.42,-6.3,;9.87,-6.69,)| Show InChI InChI=1S/C24H32N4O7S/c25-17-8-6-16(7-9-17)21(22(30)24(32)33)26-23(31)19-11-10-18-12-27(13-20(29)28(18)19)36(34,35)14-15-4-2-1-3-5-15/h1-5,16-19,21H,6-14,25H2,(H,26,31)(H,32,33)/t16-,17-,18-,19-,21?/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
BioChem Pharma Inc.
Curated by ChEMBL
| Assay Description
In vitro activity of the compound against human alpha trypsin was determined |
Bioorg Med Chem Lett 11: 287-90 (2001)
BindingDB Entry DOI: 10.7270/Q2P55MS6 |
More data for this
Ligand-Target Pair | |
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