Found 2 hits of ki for monomerid = 50121463 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Gonadotropin-releasing hormone receptor
(Homo sapiens (Human)) | BDBM50121463
(5-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphth...)Show SMILES Cc1cc2c(cc1Cc1ccc(o1)C(=O)NCC1CCC(CNc3ncccn3)CC1)C(C)(C)CCC2(C)C |(-1.64,-16.7,;-3,-15.99,;-4.37,-16.7,;-5.73,-15.99,;-5.73,-14.55,;-4.37,-13.84,;-3,-14.54,;-1.65,-13.82,;-.28,-14.53,;-.28,-15.97,;2.44,-15.99,;2.44,-14.54,;1.08,-13.82,;3.81,-13.82,;3.81,-12.38,;5.17,-14.55,;6.66,-13.66,;8.16,-14.5,;9.65,-13.61,;11.17,-14.45,;11.2,-16.18,;12.71,-17.02,;14.19,-16.13,;15.6,-17.12,;15.46,-18.85,;16.88,-19.84,;18.43,-19.1,;18.58,-17.37,;17.17,-16.39,;9.71,-17.04,;8.2,-16.23,;-7.08,-13.82,;-8.46,-13.11,;-5.73,-13.1,;-8.43,-14.55,;-8.43,-15.99,;-7.08,-16.7,;-5.73,-17.41,;-8.46,-17.41,)| Show InChI InChI=1S/C33H44N4O2/c1-22-17-27-28(33(4,5)14-13-32(27,2)3)19-25(22)18-26-11-12-29(39-26)30(38)36-20-23-7-9-24(10-8-23)21-37-31-34-15-6-16-35-31/h6,11-12,15-17,19,23-24H,7-10,13-14,18,20-21H2,1-5H3,(H,36,38)(H,34,35,37) | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development-La Jolla/Agouron Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards human gonadotropin-releasing hormone receptor |
Bioorg Med Chem Lett 12: 3635-9 (2002)
BindingDB Entry DOI: 10.7270/Q2XK8DXZ |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50121463
(5-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphth...)Show SMILES Cc1cc2c(cc1Cc1ccc(o1)C(=O)NCC1CCC(CNc3ncccn3)CC1)C(C)(C)CCC2(C)C |(-1.64,-16.7,;-3,-15.99,;-4.37,-16.7,;-5.73,-15.99,;-5.73,-14.55,;-4.37,-13.84,;-3,-14.54,;-1.65,-13.82,;-.28,-14.53,;-.28,-15.97,;2.44,-15.99,;2.44,-14.54,;1.08,-13.82,;3.81,-13.82,;3.81,-12.38,;5.17,-14.55,;6.66,-13.66,;8.16,-14.5,;9.65,-13.61,;11.17,-14.45,;11.2,-16.18,;12.71,-17.02,;14.19,-16.13,;15.6,-17.12,;15.46,-18.85,;16.88,-19.84,;18.43,-19.1,;18.58,-17.37,;17.17,-16.39,;9.71,-17.04,;8.2,-16.23,;-7.08,-13.82,;-8.46,-13.11,;-5.73,-13.1,;-8.43,-14.55,;-8.43,-15.99,;-7.08,-16.7,;-5.73,-17.41,;-8.46,-17.41,)| Show InChI InChI=1S/C33H44N4O2/c1-22-17-27-28(33(4,5)14-13-32(27,2)3)19-25(22)18-26-11-12-29(39-26)30(38)36-20-23-7-9-24(10-8-23)21-37-31-34-15-6-16-35-31/h6,11-12,15-17,19,23-24H,7-10,13-14,18,20-21H2,1-5H3,(H,36,38)(H,34,35,37) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 1.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development-La Jolla/Agouron Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards rat gonadotropin-releasing hormone receptor |
Bioorg Med Chem Lett 12: 3635-9 (2002)
BindingDB Entry DOI: 10.7270/Q2XK8DXZ |
More data for this
Ligand-Target Pair | |
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