Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse)) | BDBM50156547 (4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 20: 2235-51 (2012) Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse)) | BDBM50156547 (4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counting | Bioorg Med Chem Lett 22: 396-401 (2011) Article DOI: 10.1016/j.bmcl.2011.10.109 BindingDB Entry DOI: 10.7270/Q27P8ZT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human)) | BDBM50156547 (4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute, Inc. Curated by ChEMBL | Assay Description Displacement of [3H]PGE4 from human EP4 receptor | Bioorg Med Chem Lett 18: 821-4 (2008) Article DOI: 10.1016/j.bmcl.2007.11.020 BindingDB Entry DOI: 10.7270/Q2W096SW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human)) | BDBM50156547 (4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto Curated by ChEMBL | Assay Description Binding affinity to human EP4 receptor | J Med Chem 47: 6124-7 (2004) Article DOI: 10.1021/jm049290a BindingDB Entry DOI: 10.7270/Q2P84BBQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse)) | BDBM50156547 (4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 86 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by liquid scintillation counting | Bioorg Med Chem Lett 22: 396-401 (2011) Article DOI: 10.1016/j.bmcl.2011.10.109 BindingDB Entry DOI: 10.7270/Q27P8ZT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse)) | BDBM50156547 (4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 86 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 20: 2235-51 (2012) Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM50156547 (4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute, Inc. Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from human EP2 receptor | Bioorg Med Chem Lett 18: 821-4 (2008) Article DOI: 10.1016/j.bmcl.2007.11.020 BindingDB Entry DOI: 10.7270/Q2W096SW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM50156547 (4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto Curated by ChEMBL | Assay Description Binding affinity to human EP2 receptor | J Med Chem 47: 6124-7 (2004) Article DOI: 10.1021/jm049290a BindingDB Entry DOI: 10.7270/Q2P84BBQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse)) | BDBM50156547 (4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 20: 2235-51 (2012) Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse)) | BDBM50156547 (4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by liquid scintillation counting | Bioorg Med Chem Lett 22: 396-401 (2011) Article DOI: 10.1016/j.bmcl.2011.10.109 BindingDB Entry DOI: 10.7270/Q27P8ZT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP1 subtype (Mus musculus (Mouse)) | BDBM50156547 (4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 20: 2235-51 (2012) Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP1 subtype (Mus musculus (Mouse)) | BDBM50156547 (4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 20 mins by liquid scintillation counting | Bioorg Med Chem Lett 22: 396-401 (2011) Article DOI: 10.1016/j.bmcl.2011.10.109 BindingDB Entry DOI: 10.7270/Q27P8ZT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human)) | BDBM50156547 (4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto Curated by ChEMBL | Assay Description Binding affinity to human EP3 receptor | J Med Chem 47: 6124-7 (2004) Article DOI: 10.1021/jm049290a BindingDB Entry DOI: 10.7270/Q2P84BBQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human)) | BDBM50156547 (4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto Curated by ChEMBL | Assay Description Binding affinity to human EP1 receptor | J Med Chem 47: 6124-7 (2004) Article DOI: 10.1021/jm049290a BindingDB Entry DOI: 10.7270/Q2P84BBQ | |||||||||||
More data for this Ligand-Target Pair |