Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50163069 (1-Benzenesulfonyl-5-chloro-3-((R)-1-methyl-pyrroli...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Suven Life Sciences Ltd Curated by ChEMBL | Assay Description Binding affinity to human 5-HT6 receptor | Bioorg Med Chem Lett 22: 6980-5 (2012) Article DOI: 10.1016/j.bmcl.2012.06.002 BindingDB Entry DOI: 10.7270/Q2QZ2C3F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50163069 (1-Benzenesulfonyl-5-chloro-3-((R)-1-methyl-pyrroli...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cells | J Med Chem 57: 7160-81 (2014) Article DOI: 10.1021/jm5003952 BindingDB Entry DOI: 10.7270/Q2X92CZZ | |||||||||||
More data for this Ligand-Target Pair |