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Compile Data Set for Download or QSAR

Found 2 hits of ki for monomerid = 50186802   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))
BDBM50186802
PNG
(CHEMBL211285 | N-(3-chloro-4-fluoro-phenyl)-2-{[4-...)
Show SMILES CN(CC(=O)Nc1ccc(F)c(Cl)c1)C1(CCN(CC1)C1CCCC1)c1ccc(cc1)-c1cccc(c1)C#N
Show InChI InChI=1S/C32H34ClFN4O/c1-37(22-31(39)36-27-13-14-30(34)29(33)20-27)32(15-17-38(18-16-32)28-7-2-3-8-28)26-11-9-24(10-12-26)25-6-4-5-23(19-25)21-35/h4-6,9-14,19-20,28H,2-3,7-8,15-18,22H2,1H3,(H,36,39)
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PC cid
PC sid
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Similars

Article
PubMed
4n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity at human MCHR1 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assay


Bioorg Med Chem Lett 16: 3668-73 (2006)


Article DOI: 10.1016/j.bmcl.2006.04.061
BindingDB Entry DOI: 10.7270/Q2251HT9
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 2


(Homo sapiens (Human))
BDBM50186802
PNG
(CHEMBL211285 | N-(3-chloro-4-fluoro-phenyl)-2-{[4-...)
Show SMILES CN(CC(=O)Nc1ccc(F)c(Cl)c1)C1(CCN(CC1)C1CCCC1)c1ccc(cc1)-c1cccc(c1)C#N
Show InChI InChI=1S/C32H34ClFN4O/c1-37(22-31(39)36-27-13-14-30(34)29(33)20-27)32(15-17-38(18-16-32)28-7-2-3-8-28)26-11-9-24(10-12-26)25-6-4-5-23(19-25)21-35/h4-6,9-14,19-20,28H,2-3,7-8,15-18,22H2,1H3,(H,36,39)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
>3.00E+3n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity at human MCHR2 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assay


Bioorg Med Chem Lett 16: 3668-73 (2006)


Article DOI: 10.1016/j.bmcl.2006.04.061
BindingDB Entry DOI: 10.7270/Q2251HT9
More data for this
Ligand-Target Pair