Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50216491 (5-benzyl-6-(4-phenylpiperidin-1-yl)pyrimidine-2,4(...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Corcept Therapeutics Curated by ChEMBL | Assay Description Displacement of [3H]dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus after 18 hrs by scintillation counting anal... | Bioorg Med Chem Lett 22: 7376-80 (2012) Article DOI: 10.1016/j.bmcl.2012.10.074 BindingDB Entry DOI: 10.7270/Q26111GW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50216491 (5-benzyl-6-(4-phenylpiperidin-1-yl)pyrimidine-2,4(...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 8.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd Curated by ChEMBL | Assay Description Displacement of [3H]dexamethasone from human recombinant GR | Bioorg Med Chem Lett 17: 4901-5 (2007) Article DOI: 10.1016/j.bmcl.2007.06.036 BindingDB Entry DOI: 10.7270/Q21Z444J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50216491 (5-benzyl-6-(4-phenylpiperidin-1-yl)pyrimidine-2,4(...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 93 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd Curated by ChEMBL | Assay Description Antagonist activity at human GR | Bioorg Med Chem Lett 17: 4901-5 (2007) Article DOI: 10.1016/j.bmcl.2007.06.036 BindingDB Entry DOI: 10.7270/Q21Z444J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50216491 (5-benzyl-6-(4-phenylpiperidin-1-yl)pyrimidine-2,4(...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 93 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Corcept Therapeutics Curated by ChEMBL | Assay Description Antagonist activity at glucocorticoid receptor in human SW1353 cells assessed as inhibition of dexamethasone-induced luciferase expression after 16 h... | Bioorg Med Chem Lett 22: 7376-80 (2012) Article DOI: 10.1016/j.bmcl.2012.10.074 BindingDB Entry DOI: 10.7270/Q26111GW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mineralocorticoid receptor (Homo sapiens (Human)) | BDBM50216491 (5-benzyl-6-(4-phenylpiperidin-1-yl)pyrimidine-2,4(...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 930 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd Curated by ChEMBL | Assay Description Displacement of [3H]aldosterone from mineralocorticoid receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 4901-5 (2007) Article DOI: 10.1016/j.bmcl.2007.06.036 BindingDB Entry DOI: 10.7270/Q21Z444J | |||||||||||
More data for this Ligand-Target Pair |